Interactor 1: PEN2 (Q86BE9)
Gamma-secretase subunit pen-2 (Presenilin enhancer protein 2)
Gene: pen-2
Interactor 2: NICA (Q9VC27)
Nicastrin
Gene: Nct
Species: Drosophila melanogaster
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20421416 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ncstrn_small~PEN-2 |
| Common GO terms | GO:0005770 - late endosome GO:0006509 - membrane protein ectodomain proteolysis GO:0007219 - Notch signaling pathway GO:0007220 - Notch receptor processing GO:0016485 - protein processing and 4 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
