HitPredict

Interactor 1: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Interactor 2: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	16678097, 21481793
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1084 Hs			1 881
+	Cl
		47458 A0A8C0SSK1_CANLF (1-1084): 3.64e-93: 323: 85.60		A0A8C0RWE0_CANLF (31-881): 5.18e-129: 412: 89.42
+	Hs
		1197012 AMOT_HUMAN (1-1084): 2.95e-100: 343: 100.00		RHG24_HUMAN (181-631): 3.51e-68: 243: 19.87
+	Hs
		212759 SMCA4_HUMAN (46-595): 7.56e-34: 143: 13.45		SRGP3_HUMAN (13-738): 7.28e-82: 287: 15.65
+	Hs
		772843 MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38		RHG21_HUMAN (10-685): 2.4e-70: 256: 16.32
+	Hs
		270816 ROCK2_HUMAN (363-853): 4.77e-18: 92.2: 12.75		RHG21_HUMAN (10-685): 2.4e-70: 256: 16.32
+	Hs
		772900 MYH9_HUMAN (358-774): 8.67e-19: 94.9: 14.38		RHG24_HUMAN (181-631): 3.51e-68: 243: 19.87
+	Hs
		1123665 DCTN1_HUMAN (510-863): 1.71e-09: 64.5: 14.85		RHG21_HUMAN (10-685): 2.4e-70: 256: 16.32
+	Hs
		773225 MYH10_HUMAN (389-818): 6.65e-13: 75.8: 18.35		RHG24_HUMAN (181-631): 3.51e-68: 243: 19.87
+	Mm
		1225301 ITSN1_MOUSE (568-1069): 2.14e-09: 64.2: 8.02		RHG30_MOUSE (250-442): 1.88e-18: 92.8: 31.66