HitPredict

Interactor 1: TM11B (Q86T26)
Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5)
Gene: TMPRSS11B

Interactor 2: HMR1 (Q95460)
Major histocompatibility complex class I-related gene protein (MHC class I-related gene protein) (Class I histocompatibility antigen-like protein)
Gene: MR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~Trypsin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 341
+	Hs
		382468 TM11B_HUMAN (1-416): 0: 516: 100.00		HLAA_HUMAN (5-339): 2.41e-139: 401: 35.71
+	Hs
		354499 TM11B_HUMAN (1-416): 0: 516: 100.00		HLAB_HUMAN (5-309): 9.48e-127: 369: 36.39
+	Hs
		488277 TM11B_HUMAN (1-416): 0: 516: 100.00		HLAC_HUMAN (5-306): 2.29e-123: 360: 37.06
+	Hs
		673966 TM11B_HUMAN (1-416): 0: 516: 100.00		HLAF_HUMAN (18-339): 1.27e-118: 347: 35.35
+	Hs
		177778 TMPS2_HUMAN (70-414): 1.17e-106: 325: 28.94		HLAA_HUMAN (5-339): 2.41e-139: 401: 35.71
+	Hs
		382369 TMPS3_HUMAN (158-414): 6.93e-107: 324: 38.08		HLAA_HUMAN (5-339): 2.41e-139: 401: 35.71
+	Hs
		382540 TMPS4_HUMAN (143-413): 4.83e-103: 314: 34.93		HLAA_HUMAN (5-339): 2.41e-139: 401: 35.71
+	Hs
		177798 TMPS2_HUMAN (70-414): 1.17e-106: 325: 28.94		HLAC_HUMAN (5-306): 2.29e-123: 360: 37.06
+	Hs
		1278676 ST14_HUMAN (168-416): 1.32e-96: 309: 36.15		HMR1_HUMAN (1-341): 3.87e-126: 366: 100.00
+	Hs
		488398 TMPS4_HUMAN (143-413): 4.83e-103: 314: 34.93		HLAC_HUMAN (5-306): 2.29e-123: 360: 37.06
+	Hs
		570394 ST14_HUMAN (168-416): 1.32e-96: 309: 36.15		HLAG_HUMAN (5-309): 1.66e-125: 365: 36.39
+	Hs
		488430 ST14_HUMAN (168-416): 1.32e-96: 309: 36.15		HLAC_HUMAN (5-306): 2.29e-123: 360: 37.06