Protein: EPL1
Enhancer of polycomb-like protein 1

Gene: EPL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: P43572

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006338 - chromatin remodeling
GO:0006351 - DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849813

ESA1
Histone acetyltransferase ESA1

26

10

Small-scale

0.990

High

805126

YNG2
Chromatin modification-related protein YNG2

16

5

Small-scale

0.984

High

849811

EAF1
Chromatin modification-related protein EAF1

18

1

Small-scale

0.764

High

849801

AF9
Protein AF-9 homolog

18

3

Small-scale

0.764

High

849805

ARP4
Actin-related protein 4

18

6

Small-scale

0.763

High

805190

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

14

3

Small-scale

0.760

High

849798

SWC4
SWR1-complex protein 4

14

7

Small-scale

0.760

High

849816

EAF3
Chromatin modification-related protein EAF3

14

5

Small-scale

0.760

High

849803

ACT
Actin

11

2

Small-scale

0.756

High

849800

EAF7
Chromatin modification-related protein EAF7

10

1

Small-scale

0.754

High

816616

EAF5
Chromatin modification-related protein EAF5

12

0

Small-scale

0.725

High

849797

EAF6
Chromatin modification-related protein EAF6

7

0

Small-scale

0.711

High

382168

H4
Histone H4

4

2

Small-scale

0.673

High

419779

H2A2
Histone H2A.2

3

1

Small-scale

0.643

High

381143

H2B1
Histone H2B.1

3

8

Small-scale

0.641

High

849804

H3
Histone H3

3

0

Small-scale

0.606

High

828487

SA185
SIT4-associating protein SAP185

2

0

High-throughput

0.602

High

849817

H2AZ
Histone H2A.Z

2

4

Small-scale

0.601

High

419447

H2A1
Histone H2A.1

2

1

Small-scale

0.571

High

849808

HMO1
High mobility group protein 1

2

0

Small-scale

0.563

High

524310

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

626515

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.513

High

722034

XPO1
Exportin-1

1

0

High-throughput

0.513

High

812157

IFH1
Protein IFH1

1

1

Small-scale

0.501

High

849796

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.493

High

395250

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.480

High

408421

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.480

High

381544

H2B2
Histone H2B.2

1

8

Small-scale

0.479

High

849802

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

816997

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

707422

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734437

BTAF1
TATA-binding protein-associated factor MOT1

1

0

Small-scale

0.458

High

735032

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

740967

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

747915

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

763924

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

800717

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.458

High

826590

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

849795

EPL1
Enhancer of polycomb-like protein 1

1

0

Small-scale

0.458

High

849806

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

Small-scale

0.458

High

849809

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

849814

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

526982

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

676099

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

727121

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741813

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

754216

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.445

High

849812

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

402038

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.426

High

448183

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

545298

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

739669

SPT16
FACT complex subunit SPT16

1

0

Small-scale

0.426

High

781753

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

849815

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.426

High

752405

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

779549

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

823105

ATG3
Autophagy-related protein 3

1

0

Small-scale

0.249

Low

849810

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

849807

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

626787

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

822454

TBP6
Probable 26S proteasome subunit YTA6

1

0

High-throughput

0.232

Low

849799

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025