HitPredict

Interactor 1: WDR5B (Q86VZ2)
WD repeat-containing protein 5B
Gene: WDR5B

Interactor 2: WDR6 (Q9NNW5)
tRNA (34-2'-O)-methyltransferase regulator WDR6 (WD repeat-containing protein 6)
Gene: WDR6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 330 Hs			1 1121
+	Hs
		903109 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		929603 FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		254111 FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40		WDR1_HUMAN (538-1119): 1.07e-31: 134: 9.41
+	Sp
		999838 TUP11_SCHPO (1-289): 8.64e-92: 287: 24.68		TUP11_SCHPO (759-1119): 9.81e-29: 125: 16.94
+	Hs
		903551 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		NLE1_HUMAN (2-141): 9.17e-25: 111: 8.05
+	Dm
		1358845 WDS_DROME (2-286): 9.88e-95: 286: 29.90		WDS_DROME (866-1120): 3.57e-18: 89.7: 12.55
+	Sp
		999842 TUP11_SCHPO (1-289): 8.64e-92: 287: 24.68		TUP12_SCHPO (126-327): 1.91e-15: 82.9: 17.96
+	Hs
		903418 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		903174 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		TBL3_HUMAN (12-118): 1.81e-11: 70.5: 7.34
+	Hs
		1281292 FBXW7_HUMAN (1-319): 1.47e-88: 281: 28.40		FBXW7_HUMAN (603-914): 3.98e-13: 76: 13.75
+	Hs
		903428 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		903349 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		WDR5B_HUMAN (390-646): 2.24e-09: 62.2: 12.78
+	Hs
		903077 WDR5_HUMAN (2-286): 4.02e-95: 287: 29.21		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		929579 POC1B_HUMAN (154-330): 5.19e-47: 166: 20.90		RACK1_HUMAN (196-523): 2.91e-47: 173: 17.21
+	Hs
		197071 PRP4_HUMAN (125-330): 6.22e-50: 175: 22.43		SNR40_HUMAN (200-348): 7.65e-10: 64: 26.58
+	Hs
		196984 PRP4_HUMAN (125-330): 6.22e-50: 175: 22.43		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53
+	Hs
		1240442 POC1B_HUMAN (154-330): 5.19e-47: 166: 20.90		POC1A_HUMAN (727-992): 5.31e-10: 64.8: 12.78
+	Hs
		209416 PLRG1_HUMAN (158-328): 2.42e-40: 149: 28.66		WDR5_HUMAN (390-646): 7.51e-09: 60.7: 13.53