HitPredict

Interactor 1: ANKL2 (Q86XL3)
Ankyrin repeat and LEM domain-containing protein 2 (LEM domain-containing protein 4)
Gene: ANKLE2

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ras
Common GO terms	GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 938 Hs			1 618
+	Hs
		545477 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		892466 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		894183 ANKL2_HUMAN (1-938): 0: 1602: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		1070277 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		951128 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		914185 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		900653 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		436387 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120519 ANKL2_HUMAN (1-938): 0: 1602: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89