HitPredict

Interactor 1: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Interactor 2: YTHD2 (Q9Y5A9)
YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Gene: YTHDF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 39501047
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2229 Hs			1 579
+	Hs
		1206480 PRC2B_HUMAN (1-2229): 0: 638: 100.00		YTHD3_HUMAN (1-562): 1.94e-150: 447: 65.56
+	Hs
		1206534 PRC2B_HUMAN (1-2229): 0: 638: 100.00		YTHD1_HUMAN (1-579): 1.7e-139: 417: 62.20
+	Hs
		1121933 EIF3A_HUMAN (962-1409): 7.88e-26: 119: 14.63		YTHD2_HUMAN (1-579): 1.25e-177: 516: 100.00
+	Hs
		1491482 PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67		YTHD2_HUMAN (1-579): 1.25e-177: 516: 100.00
+	Hs
		1401473 CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32		YTHD2_HUMAN (1-579): 1.25e-177: 516: 100.00
+	Hs
		875845 PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67		YTHD2_HUMAN (1-579): 1.25e-177: 516: 100.00
+	Hs
		1280783 PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67		YTHD3_HUMAN (1-562): 1.94e-150: 447: 65.56
+	Hs
		1121870 EIF3A_HUMAN (962-1409): 7.88e-26: 119: 14.63		YTHD1_HUMAN (1-579): 1.7e-139: 417: 62.20
+	Hs
		875702 PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67		YTHD3_HUMAN (1-562): 1.94e-150: 447: 65.56
+	Hs
		1418774 PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67		YTHD1_HUMAN (1-579): 1.7e-139: 417: 62.20
+	Hs
		875773 PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67		YTHD1_HUMAN (1-579): 1.7e-139: 417: 62.20
+	Hs
		1401394 CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32		YTDC2_HUMAN (285-556): 1.62e-54: 202: 20.50
+	Hs
		925743 CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32		SC24C_HUMAN (42-405): 4.05e-36: 146: 15.51
+	Dm
		119660 M9PB30_DROME (13-613): 1.84e-18: 95.5: 8.96		M9PB30_DROME (1-283): 4.94e-15: 81.1: 9.39
+	Hs
		1130579 NCOA6_HUMAN (3-935): 5.4e-13: 77.4: 8.33		KMT2C_HUMAN (7-383): 1.98e-13: 76.1: 14.92
+	Hs
		161491 KMT2D_HUMAN (1599-2221): 1.48e-10: 69.3: 10.43		KMT2C_HUMAN (7-383): 1.98e-13: 76.1: 14.92
+	Mm
		1455913 PCLO_MOUSE (7-1590): 8.31e-11: 70.1: 6.65		PCLO_MOUSE (39-306): 1.24e-09: 63.8: 14.49