HitPredict

Interactor 1: Q8CJ76 (Q8CJ76)
Leukemia-associated protein MLLT1
Gene: Mllt1

Interactor 2: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17296600
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 547 Mm			1 336
+	Mm
		1321740 Q9ERL0_MOUSE (1-547): 8.5e-95: 301: 99.63		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Mm
		57329 AF9_MOUSE (1-547): 8.95e-82: 267: 50.62		RING2_MOUSE (1-336): 2.13e-106: 316: 100.00
+	Hs
		974511 ENL_HUMAN (1-547): 8.11e-82: 267: 83.90		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		788060 AF9_HUMAN (1-547): 5.03e-80: 263: 50.26		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		717730 ENL_HUMAN (1-547): 8.11e-82: 267: 83.90		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		974513 ENL_HUMAN (1-547): 8.11e-82: 267: 83.90		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56
+	Hs
		788062 AF9_HUMAN (1-547): 5.03e-80: 263: 50.26		PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56
+	Hs
		1264788 TITIN_HUMAN (137-507): 1.07e-09: 63.6: 10.26		RING2_HUMAN (1-336): 2.74e-106: 315: 99.70
+	Hs
		987995 KMT2C_HUMAN (96-474): 1.71e-26: 117: 12.63		RING1_HUMAN (10-336): 3.44e-66: 215: 51.75
+	Hs
		749592 NIPBL_HUMAN (124-492): 1.02e-26: 117: 12.76		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93
+	Hs
		718055 TITIN_HUMAN (137-507): 1.07e-09: 63.6: 10.26		BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83
+	Hs
		1264797 TITIN_HUMAN (137-507): 1.07e-09: 63.6: 10.26		TRI55_HUMAN (42-318): 5.67e-37: 141: 13.42
+	Hs
		749718 TITIN_HUMAN (137-507): 1.07e-09: 63.6: 10.26		BRCA1_HUMAN (36-213): 1.88e-33: 132: 25.93