HitPredict

Interactor 1: APBB1 (O00213)
Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65)
Gene: APBB1

Interactor 2: APLP2 (Q06481)
Amyloid beta precursor like protein 2 (APPH) (Amyloid beta (A4) precursor-like protein 2) (Amyloid protein homolog) (Amyloid-like protein 2) (APLP-2) (CDEI box-binding protein) (CDEBP) (Sperm membrane protein YWK-II)
Gene: APLP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.923

The method score is based on:

Property Details
Experiments 28514442, 8855266, 10081969, 33961781, 9461550
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains APP_amyloid~PID
Common GO terms GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0007409 - axonogenesis
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 710
Hs

1 763
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024