HitPredict

Interactor 1: APC2 (Q8H1U5)
Anaphase-promoting complex subunit 2 (Cyclosome subunit 2)
Gene: APC2

Interactor 2: FZR3 (Q8LPL5)
Protein FIZZY-RELATED 3 (Cell cycle switch protein CCS52B)
Gene: FZR3

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	20706207
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 865 At			1 481
+	At
		1210827 APC2_ARATH (1-865): 0: 902: 100.00		FZR1_ARATH (4-481): 6.07e-101: 312: 59.50
+	At
		1210833 APC2_ARATH (1-865): 0: 902: 100.00		CDC21_ARATH (263-480): 2.16e-37: 144: 21.21
+	At
		1210823 APC2_ARATH (1-865): 0: 902: 100.00		FZR2_ARATH (263-480): 1.23e-33: 134: 20.18
+	Hs
		1356164 ANC2_HUMAN (49-865): 0: 674: 30.43		FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64
+	Hs
		903590 ANC2_HUMAN (49-865): 0: 674: 30.43		WDR5_HUMAN (4-325): 1.72e-48: 171: 16.31
+	Mm
		1207526 ANC2_MOUSE (49-865): 0: 678: 30.67		CDC20_MOUSE (263-480): 9.46e-39: 148: 18.42
+	Hs
		1017462 ANC2_HUMAN (49-865): 0: 674: 30.43		CDC20_HUMAN (263-480): 3.22e-37: 144: 19.21
+	Mm
		1207527 ANC2_MOUSE (49-865): 0: 678: 30.67		FZR1_MOUSE (94-293): 2.47e-17: 86.2: 13.53
+	Dm
		1376270 Q9W1E5_DROME (76-865): 0: 641: 29.43		Q9W4H9_DROME (304-480): 2.7e-25: 110: 19.13
+	Hs
		1041277 CUL1_HUMAN (181-857): 3.33e-137: 428: 14.01		FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64
+	Mm
		1257398 CUL1_MOUSE (181-857): 3.06e-137: 428: 14.01		FBXW7_MOUSE (96-409): 1.8e-61: 214: 15.48
+	Hs
		1041133 CUL1_HUMAN (181-857): 3.33e-137: 428: 14.01		FBXW7_HUMAN (136-409): 5.68e-61: 213: 17.31
+	Hs
		245601 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		TBL1X_HUMAN (34-417): 5.86e-63: 216: 14.43
+	Hs
		1043499 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		FBXW7_HUMAN (136-409): 5.68e-61: 213: 17.31
+	Hs
		1043509 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		SNR40_HUMAN (66-412): 6.11e-61: 204: 16.99
+	Hs
		903206 CUL1_HUMAN (181-857): 3.33e-137: 428: 14.01		WDR5_HUMAN (4-325): 1.72e-48: 171: 16.31
+	Hs
		903209 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		WDR5_HUMAN (4-325): 1.72e-48: 171: 16.31
+	Hs
		1017377 CUL1_HUMAN (181-857): 3.33e-137: 428: 14.01		CDC20_HUMAN (263-480): 3.22e-37: 144: 19.21
+	Hs
		1043441 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		WDR5B_HUMAN (416-479): 1.07e-09: 61.9: 18.46
+	Hs
		1043469 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		POC1B_HUMAN (424-480): 2.07e-09: 61.5: 24.14