HitPredict

Interactor 1: Q8IML3 (Q8IML3)
V-type proton ATPase subunit a
Gene: Vha100-1

Interactor 2: Q9VE75 (Q9VE75)
V-type proton ATPase subunit a
Gene: Vha100-2

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	V_ATPase_I~V_ATPase_I
Common GO terms	GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain GO:0005886 - plasma membrane GO:0007035 - vacuolar acidification GO:0016471 - vacuolar proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism and 1 others more... GO:0051117 - ATPase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 836 Dm			1 834
+	Hs
		1335304 VPP4_HUMAN (1-832): 0: 1233: 53.46		VPP2_HUMAN (1-827): 0: 1142: 44.41
+	Hs
		1274159 VPP1_HUMAN (1-829): 0: 1225: 60.00		VPP2_HUMAN (1-827): 0: 1142: 44.41
+	Hs
		1035679 VPP1_HUMAN (1-829): 0: 1225: 60.00		VPP3_HUMAN (1-829): 0: 1044: 42.49
+	Hs
		1035691 VPP2_HUMAN (1-826): 0: 1155: 45.20		VPP3_HUMAN (1-829): 0: 1044: 42.49
+	Sc
		693186 VPP1_YEAST (3-824): 0: 1037: 39.15		VPP1_YEAST (4-825): 0: 1011: 39.17
+	Sc
		693194 VPP1_YEAST (3-824): 0: 1037: 39.15		VPP2_YEAST (4-829): 0: 916: 35.20