HitPredict

Interactor 1: Q5U8S2 (Q5U8S2)
Syntaxin 10
Gene: STX10

Interactor 2: VTI1A (Q96AJ9)
Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2)
Gene: VTI1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0006886 - intracellular protein transport
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 217
+	Hs
		249887 STX10_HUMAN (1-226): 3.31e-72: 222: 99.12		VTI1A_HUMAN (1-217): 2.22e-63: 197: 100.00
+	Mm
		313465 STX6_MOUSE (1-226): 5.34e-62: 196: 59.91		VTI1A_MOUSE (1-217): 8.13e-66: 204: 94.93
+	Rn
		1224613 STX6_RAT (1-226): 2.52e-62: 197: 59.91		VTI1A_RAT (1-217): 2.14e-60: 190: 93.30
+	Hs
		226165 STX6_HUMAN (1-226): 2.37e-59: 190: 59.05		VTI1A_HUMAN (1-217): 2.22e-63: 197: 100.00
+	At
		1375200 SYP61_ARATH (2-226): 4.57e-60: 191: 21.05		VTI12_ARATH (1-215): 8.95e-62: 193: 28.51
+	Hs
		249908 STX10_HUMAN (1-226): 3.31e-72: 222: 99.12		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	Mm
		1362332 STX6_MOUSE (1-226): 5.34e-62: 196: 59.91		Q91XH6_MOUSE (2-217): 4.07e-54: 174: 29.02
+	Hs
		160226 STX6_HUMAN (1-226): 2.37e-59: 190: 59.05		GOSR2_HUMAN (5-212): 2.09e-53: 172: 14.09
+	At
		1456167 SYP51_ARATH (2-225): 2.66e-50: 166: 20.09		VTI11_ARATH (1-216): 4.46e-60: 189: 32.13
+	Hs
		226247 STX6_HUMAN (1-226): 2.37e-59: 190: 59.05		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	Hs
		1383316 STX8_HUMAN (3-225): 1.88e-42: 146: 17.94		VTI1A_HUMAN (1-217): 2.22e-63: 197: 100.00
+	Hs
		160348 STX8_HUMAN (3-225): 1.88e-42: 146: 17.94		GOSR2_HUMAN (5-212): 2.09e-53: 172: 14.09
+	Hs
		1459042 STX8_HUMAN (3-225): 1.88e-42: 146: 17.94		VTI1B_HUMAN (2-216): 3.27e-47: 157: 27.80
+	Dm
		1487160 Q9VV76_DROME (5-225): 7.64e-35: 126: 14.03		Q9W0N6_DROME (3-214): 2.02e-50: 165: 36.53
+	Dm
		1484998 Q9VV76_DROME (5-225): 7.64e-35: 126: 14.03		GOSR2_DROME (5-212): 3.59e-50: 164: 18.14
+	Sc
		1042336 TLG1_YEAST (2-226): 3.33e-31: 116: 18.67		VTI1_YEAST (1-196): 6.11e-38: 132: 31.84
+	Sc
		748237 VAM7_YEAST (63-215): 4.24e-21: 91.8: 18.30		VTI1_YEAST (1-196): 6.11e-38: 132: 31.84
+	Dm
		84886 Q9VV76_DROME (5-225): 7.64e-35: 126: 14.03		B7Z0M0_DROME (109-214): 1.84e-15: 71.7: 27.36