HitPredict

Interactor 1: Z3H7A (Q8IWR0)
Zinc finger CCCH domain-containing protein 7A
Gene: ZC3H7A

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30995489, 29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0035196 - miRNA processing GO:0035198 - miRNA binding GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 971 Hs			1 859
+	Hs
		1219264 Z3H7A_HUMAN (1-971): 0: 1124: 100.00		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1219242 Z3H7A_HUMAN (1-971): 0: 1124: 100.00		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		972609 FKBP4_HUMAN (3-221): 3.61e-47: 177: 13.90		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		1035042 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		858682 PPP5_HUMAN (23-214): 3.34e-44: 169: 19.90		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1035043 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		858668 PPP5_HUMAN (23-214): 3.34e-44: 169: 19.90		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1035002 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1035009 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		AGO4_HUMAN (16-859): 0: 1145: 78.51
+	Hs
		59978 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		A4FVC0_HUMAN (72-859): 0: 1130: 100.00
+	Ce
		108406 STIP1_CAEEL (15-229): 1.03e-35: 140: 16.28		G5EGR6_CAEEL (19-859): 0: 1102: 67.09
+	Hs
		1294944 Q9BPW0_HUMAN (23-214): 3.24e-44: 169: 19.90		PIWL1_HUMAN (23-826): 0: 751: 22.45
+	Hs
		1034966 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		PIWL1_HUMAN (23-826): 0: 751: 22.45
+	Hs
		1253318 Q9BPW0_HUMAN (23-214): 3.24e-44: 169: 19.90		PIWL2_HUMAN (5-821): 0: 735: 21.74
+	Hs
		1034939 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		PIWL2_HUMAN (5-821): 0: 735: 21.74
+	Hs
		1189711 Q9BPW0_HUMAN (23-214): 3.24e-44: 169: 19.90		PIWL4_HUMAN (22-822): 0: 686: 22.07
+	Hs
		1034913 FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54		PIWL4_HUMAN (22-822): 0: 686: 22.07
+	Dm
		1186011 Q9VPN5_DROME (40-400): 1.07e-37: 150: 12.43		AGO3_DROME (31-826): 0: 638: 20.89
+	Dm
		1369530 Q9VPN5_DROME (40-400): 1.07e-37: 150: 12.43		PIWI_DROME (5-826): 0: 628: 21.56
+	Hs
		1135548 Q9BPW0_HUMAN (23-214): 3.24e-44: 169: 19.90		Q5TA56_HUMAN (5-218): 4.02e-88: 280: 62.33