Interactor 1: NELFD (Q8IXH7)
Negative elongation factor C/D (NELF-C/D) (TH1-like protein)
Gene: NELFCD

Interactor 2: NELFA (Q9H3P2)
Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein)
Gene: NELFA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 32296183, 24981860, 20305087, 25416956, 26496610, 28514442, 12612062, 33961781, unassigned1304, 20211142
Identification Methods two hybrid, affinity chromatography technology, pull down, validated two hybrid, two hybrid array, two hybrid prey pooling approach, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0032021 - NELF complex
GO:0034244 - negative regulation of transcription elongation by RNA polymerase II
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 590
Hs

1 528
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024