Protein: ANK1
Ankyrin-1 (ANK-1) (Ankyrin-R) (Erythrocyte ankyrin)

Gene: ANK1
Organism: Homo sapiens
Interactions: 47
UniProt ID: P16157

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

592939

OBSCN
Obscurin

4

7

Small-scale

0.908

High

388363

B3AT
Band 3 anion transport protein

3

1

Small-scale

0.817

High

139373

NCHL1
Neural cell adhesion molecule L1-like protein

2

8

High-throughput

0.811

High

592949

TITIN
Titin

2

5

Small-scale

0.793

High

386434

SPTA1
Spectrin alpha chain, erythrocytic 1

2

20

Small-scale

0.778

High

239298

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

19

High-throughput

0.691

High

541315

FGFR1
Fibroblast growth factor receptor 1

1

16

High-throughput

0.691

High

540235

SPTB1
Spectrin beta chain, erythrocytic

1

19

Small-scale

0.647

High

592929

RHAG
Ammonium transporter Rh type A

1

0

Small-scale

0.645

High

592930

VAC14
Protein VAC14 homolog

2

2

High-throughput

0.628

High

592951

RPGF5
Rap guanine nucleotide exchange factor 5

2

3

High-throughput

0.628

High

592955

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

6

High-throughput

0.628

High

592924

B3A3
Anion exchange protein 3

1

1

Small-scale

0.618

High

592928

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

20

Small-scale

0.618

High

592933

CUL3
Cullin-3

1

9

Small-scale

0.618

High

592941

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

380827

MYG
Myoglobin

2

2

High-throughput

0.612

High

592956

FYV1
1-phosphatidylinositol 3-phosphate 5-kinase

2

2

High-throughput

0.611

High

592938

RTP2
Receptor-transporting protein 2

2

1

High-throughput

0.606

High

592942

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

4

High-throughput

0.606

High

592923

TGFR1
TGF-beta receptor type-1

1

0

Small-scale

0.586

High

592926

EMD
Emerin

2

0

High-throughput

0.580

High

592927

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.580

High

592935

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

592950

FIG4
Polyphosphoinositide phosphatase

2

1

High-throughput

0.574

High

592932

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

9

Small-scale

0.561

High

592937

Q4KMX9
OBSCN protein

1

4

High-throughput

0.553

High

592945

KCTD6
BTB/POZ domain-containing protein KCTD6

1

11

Small-scale

0.552

High

415328

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.541

High

592934

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.536

High

592936

ANO6
Anoctamin-6

1

0

High-throughput

0.513

High

592922

RYR1
Ryanodine receptor 1

1

4

Small-scale

0.501

High

592931

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

592940

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

592946

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

592954

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

592953

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

3

High-throughput

0.445

High

105267

APRIO
Alternative prion protein

1

2

High-throughput

0.437

High

592925

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.437

High

591209

CD44
CD44 antigen

1

2

Small-scale

0.408

High

96864

E9PDH4
Phosphoinositide kinase, FYVE-type zinc finger containing

1

5

High-throughput

0.407

High

592947

NELFB
Negative elongation factor B

2

0

High-throughput

0.328

High

592943

NRM
Nurim

2

0

High-throughput

0.316

High

592944

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.316

High

592952

TM203
Transmembrane protein 203

2

0

High-throughput

0.316

High

592948

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

516251

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025