HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: WDFY3 (Q8IZQ1)
WD repeat and FYVE domain-containing protein 3 (Autophagy-linked FYVE protein) (Alfy)
Gene: WDFY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 3526
+	Hs
		914203 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		WDFY3_HUMAN (1-3526): 0: 4218: 100.00
+	Hs
		1040937 MIRO2_HUMAN (1-618): 0: 792: 100.00		MTMR3_HUMAN (3275-3521): 1.52e-39: 164: 20.00
+	Hs
		841965 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		LRBA_HUMAN (1094-1749): 6.78e-162: 567: 12.75
+	Hs
		841968 RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47		LRBA_HUMAN (1094-1749): 6.78e-162: 567: 12.75
+	Hs
		841967 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		LRBA_HUMAN (1094-1749): 6.78e-162: 567: 12.75
+	Hs
		841966 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		LRBA_HUMAN (1094-1749): 6.78e-162: 567: 12.75
+	Hs
		914229 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		NBEA_HUMAN (1094-1748): 6.36e-148: 522: 13.88
+	Hs
		894090 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		WDR81_HUMAN (2651-2991): 4.05e-71: 269: 27.73
+	Hs
		903100 RAB1A_HUMAN (416-593): 1.56e-40: 148: 18.28		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		903508 RAB1B_HUMAN (416-578): 8.51e-39: 143: 19.05		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		545577 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		894741 RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34		WDR81_HUMAN (2651-2991): 4.05e-71: 269: 27.73
+	Hs
		894344 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		1070359 RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		951257 RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		925546 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		894711 RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34		WDR5_HUMAN (2952-3290): 6.23e-71: 244: 15.32
+	Hs
		894819 RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34		MTMR4_HUMAN (3367-3520): 7.52e-55: 214: 29.07
+	Hs
		914301 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		RUFY1_HUMAN (3273-3521): 1.93e-30: 133: 23.26
+	Hs
		914153 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		NBEL2_HUMAN (1028-1577): 5.89e-15: 84.6: 11.92