HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: PDZD8 (Q8NEN9)
PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR-104)
Gene: PDZD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras
Common GO terms	GO:0005739 - mitochondrion GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 618 Hs			1 1154
+	Hs
		545506 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		892493 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		894224 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		1070308 RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		951166 RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		925446 RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		914225 RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		900703 RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		436411 RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		120545 RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89		PDZD8_HUMAN (1-1154): 0: 2032: 100.00
+	Hs
		564617 RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26		PDZD8_HUMAN (1-1154): 0: 2032: 100.00