HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 8797
+	Hs
		894227 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		SYNE1_HUMAN (1-8797): 0: 1912: 100.00
+	Hs
		974107 MIRO2_HUMAN (1-618): 0: 792: 100.00		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Hs
		1220678 MIRO2_HUMAN (1-618): 0: 792: 100.00		SPTN5_HUMAN (6622-8751): 1.41e-33: 147: 12.27
+	Hs
		545530 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		SYNE2_HUMAN (2840-8740): 2.87e-69: 265: 8.94
+	Hs
		894261 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		SYNE2_HUMAN (2840-8740): 2.87e-69: 265: 8.94
+	Hs
		164589 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12
+	Hs
		164590 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12
+	Hs
		164620 RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70		SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12
+	Hs
		545334 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Hs
		545327 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49
+	Hs
		892322 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49
+	Hs
		893910 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49
+	Hs
		545364 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		545254 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		UTRN_HUMAN (7111-8757): 2.11e-24: 117: 11.28
+	Hs
		892360 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		809091 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		UTRN_HUMAN (7111-8757): 2.11e-24: 117: 11.28
+	Hs
		893989 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		809092 CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54		UTRN_HUMAN (7111-8757): 2.11e-24: 117: 11.28
+	Hs
		297812 RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69		K0754_HUMAN (8306-8740): 1.1e-19: 101: 16.51
+	Hs
		297819 RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22		K0754_HUMAN (8306-8740): 1.1e-19: 101: 16.51