Interactor 1: SIN3A (Q60520)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Interactor 2: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16103876
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PAH~Sin3_corepress, Sin3a_C~Sin3a_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0030336 - negative regulation of cell migration
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1274
Mm

1 1098
+ Hs
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025