HitPredict - High confidence protein-protein interactions

Interactor 1: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3

Interactor 2: SIN3 (P22579)
Transcriptional regulatory protein SIN3
Gene: SIN3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	19345193, 11454208, 21179020
Identification Methods	pull down, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	PAH~Sin3_corepress, Sin3a_C~Sin3a_C
Common GO terms	GO:0000086 - G2/M transition of mitotic cell cycle GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003713 - transcription coactivator activity GO:0003714 - transcription corepressor activity and 18 others more... GO:0005634 - nucleus GO:0006303 - double-strand break repair via nonhomologous end joining GO:0006334 - nucleosome assembly GO:0006357 - regulation of transcription by RNA polymerase II GO:0016479 - negative regulation of transcription by RNA polymerase I GO:0030174 - regulation of DNA-templated DNA replication initiation GO:0032221 - Rpd3S complex GO:0033698 - Rpd3L complex GO:0034605 - cellular response to heat GO:0044804 - nucleophagy GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051301 - cell division GO:0051321 - meiotic cell cycle GO:0061186 - negative regulation of silent mating-type cassette heterochromatin formation GO:0061188 - negative regulation of rDNA heterochromatin formation GO:0070210 - Rpd3L-Expanded complex GO:0070550 - rDNA chromatin condensation GO:0070822 - Sin3-type complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	1536
Sc

1	1536

Service provided by Combinatics, Japan

Last updated: 11Aug2025