HitPredict

Interactor 1: SRC8 (Q60598)
Src substrate cortactin
Gene: Cttn

Interactor 2: HIP1R (Q9JKY5)
Huntingtin-interacting protein 1-related protein (HIP1-related protein)
Gene: HIP1R

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17318189
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005905 - clathrin-coated pit GO:0005938 - cell cortex GO:0006898 - receptor-mediated endocytosis GO:0043197 - dendritic spine and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 546 Mm			1 1068
+	Hs
		772797 SRC8_HUMAN (1-546): 5.76e-164: 479: 92.18		MYH9_HUMAN (635-1068): 5.45e-16: 85.7: 8.99
+	Hs
		1124677 SRC8_HUMAN (1-546): 5.76e-164: 479: 92.18		MY18A_HUMAN (360-823): 1.86e-14: 80.7: 17.34
+	Hs
		1124594 SRC8_HUMAN (1-546): 5.76e-164: 479: 92.18		PLEC_HUMAN (130-725): 2.21e-10: 67.3: 10.72
+	Hs
		130962 ITSN1_HUMAN (244-544): 7.88e-18: 89.8: 12.14		HIP1_HUMAN (1-1037): 5.43e-68: 249: 49.95
+	Hs
		1123627 LASP1_HUMAN (302-545): 3e-38: 143: 20.88		DCTN1_HUMAN (343-637): 2.75e-47: 186: 24.27
+	Hs
		556923 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		MYH7_HUMAN (12-889): 5.87e-31: 134: 8.54
+	Hs
		772771 MYO1E_HUMAN (175-545): 2.46e-42: 164: 14.53		MYH9_HUMAN (635-1068): 5.45e-16: 85.7: 8.99
+	Hs
		1091698 MYO1E_HUMAN (175-545): 2.46e-42: 164: 14.53		MY18A_HUMAN (360-823): 1.86e-14: 80.7: 17.34
+	Hs
		1117368 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		EEA1_HUMAN (87-656): 1.53e-20: 100: 8.41
+	Hs
		386467 SPTA1_HUMAN (140-545): 2.48e-34: 140: 16.37		EEA1_HUMAN (87-656): 1.53e-20: 100: 8.41
+	Hs
		635527 NEBU_HUMAN (218-545): 6.61e-34: 139: 18.86		EEA1_HUMAN (87-656): 1.53e-20: 100: 8.41
+	Hs
		1141981 ITSN2_HUMAN (31-545): 2.65e-31: 131: 13.73		EEA1_HUMAN (87-656): 1.53e-20: 100: 8.41
+	Hs
		772789 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		MYH9_HUMAN (635-1068): 5.45e-16: 85.7: 8.99
+	Hs
		1117429 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		MY18A_HUMAN (360-823): 1.86e-14: 80.7: 17.34
+	Hs
		1117369 SPTN1_HUMAN (141-545): 3.52e-35: 143: 14.03		PLEC_HUMAN (130-725): 2.21e-10: 67.3: 10.72
+	Hs
		386468 SPTA1_HUMAN (140-545): 2.48e-34: 140: 16.37		PLEC_HUMAN (130-725): 2.21e-10: 67.3: 10.72