HitPredict

Interactor 1: SMC5 (Q8IY18)
Structural maintenance of chromosomes protein 5 (SMC protein 5) (SMC-5) (hSMC5)
Gene: SMC5

Interactor 2: NSE1 (Q8WV22)
Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27)
Gene: NSMCE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 18086888, 36373674, 16055714
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000775 - chromosome, centromeric region
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1101
Hs

1 266
+ Hs
+ Sp
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024