Protein: IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial (EC 1.1.1.41) (Isocitric dehydrogenase) (NAD(+)-specific ICDH)

Gene: IDH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P28834

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003723 - RNA binding
GO:0004449 - isocitrate dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

657035

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

13

12

Small-scale

0.980

High

602428

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

3

High-throughput

0.618

High

477976

HSP77
Import motor subunit, mitochondrial

2

8

High-throughput

0.584

High

479970

RS6A
Small ribosomal subunit protein eS6A

2

2

High-throughput

0.584

High

543332

HSC82
ATP-dependent molecular chaperone HSC82

2

6

High-throughput

0.584

High

567941

MDHM
Malate dehydrogenase, mitochondrial

2

4

Small-scale

0.584

High

660894

MKK2
MAP kinase kinase MKK2/SSP33

1

5

High-throughput

0.536

High

660900

SPT7
Transcriptional activator SPT7

1

1

High-throughput

0.536

High

660914

RV167
Reduced viability upon starvation protein 167

1

2

High-throughput

0.536

High

660931

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

4

High-throughput

0.536

High

500303

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

0

High-throughput

0.513

High

660890

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.513

High

660908

IMB2
Importin subunit beta-2

1

4

High-throughput

0.500

High

660924

RPN14
26S proteasome regulatory subunit RPN14

1

9

High-throughput

0.500

High

439633

SPS1
Sporulation-specific protein 1

1

1

High-throughput

0.489

High

660918

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.489

High

660935

KU80
ATP-dependent DNA helicase II subunit 2

1

1

High-throughput

0.489

High

660932

AP1M1
AP-1 complex subunit mu-1-I

1

0

High-throughput

0.479

High

141202

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

357932

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.479

High

365923

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

382995

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

406852

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

407778

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

413354

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

423586

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

1

High-throughput

0.479

High

425814

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

470910

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

472061

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

480532

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.479

High

485670

IF4A
ATP-dependent RNA helicase eIF4A

1

2

High-throughput

0.479

High

490550

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.479

High

605930

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

612929

AIM17
Probable oxidoreductase AIM17

1

1

High-throughput

0.479

High

627765

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

631720

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

638661

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

641313

KAD3
GTP:AMP phosphotransferase, mitochondrial

1

1

High-throughput

0.479

High

645302

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

650209

COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1

1

High-throughput

0.479

High

660891

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

660895

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

660896

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.479

High

660897

RSSA1
Small ribosomal subunit protein uS2A

1

5

High-throughput

0.479

High

660898

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.479

High

660899

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

660903

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

660904

MIC60
MICOS complex subunit MIC60

1

2

High-throughput

0.479

High

660905

LONM
Lon protease homolog, mitochondrial

1

5

High-throughput

0.479

High

660906

GBLP
Small ribosomal subunit protein RACK1

1

7

High-throughput

0.479

High

660909

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

660913

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

660922

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

660928

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

660933

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

660934

ABF2
ARS-binding factor 2, mitochondrial

1

4

Small-scale

0.479

High

660936

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

2

High-throughput

0.479

High

660940

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.479

High

660944

RIO1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

660946

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

357225

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

660925

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

660930

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.458

High

660941

YP191
Ubiquitin carboxyl-terminal hydrolase MIY1

1

0

High-throughput

0.458

High

660919

BNI1
Protein BNI1

1

1

High-throughput

0.457

High

594298

PP11
Serine/threonine-protein phosphatase PP1-1

1

2

High-throughput

0.457

High

597799

PWP1
Periodic tryptophan protein 1

1

7

High-throughput

0.457

High

632518

DMC1
Meiotic recombination protein DMC1

1

1

High-throughput

0.457

High

660912

TCPB
T-complex protein 1 subunit beta

1

2

High-throughput

0.457

High

510511

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

660916

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

660917

ATAD2
ATPase histone chaperone YTA7

1

4

High-throughput

0.445

High

660889

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

660892

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.437

High

660893

HOG1
Mitogen-activated protein kinase HOG1

1

2

High-throughput

0.437

High

660901

SPT10
Protein SPT10

1

1

High-throughput

0.437

High

660902

SPT21
Protein SPT21

1

1

High-throughput

0.437

High

660920

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.437

High

660923

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

660927

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.437

High

660929

H3
Histone H3

1

1

High-throughput

0.437

High

660937

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.437

High

660943

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

660907

HMT1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.417

High

660911

SPT8
Transcription factor SPT8

1

1

High-throughput

0.407

High

660915

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

1

High-throughput

0.407

High

540211

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

0

High-throughput

0.279

Low

660938

RBX1
RING-box protein HRT1

1

0

High-throughput

0.279

Low

660945

HRT3
F-box protein HRT3

1

0

High-throughput

0.279

Low

660910

YHY2
Uncharacterized protein YHR182W

1

0

High-throughput

0.269

Low

660921

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

660926

YG2W
Uncharacterized protein YGR111W

1

0

High-throughput

0.249

Low

660939

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

660942

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

Small-scale

0.249

Low

392330

H2A2
Histone H2A.2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024