Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
MRE11
Double-strand break repair protein MRE11 |
43 |
2 |
Small-scale |
0.994 | High |
|
|
MDC1
Mediator of DNA damage checkpoint protein 1 |
15 |
2 |
Small-scale |
0.987 | High |
|
|
BRCA1
Breast cancer type 1 susceptibility protein |
10 |
3 |
Small-scale |
0.964 | High |
|
|
TOPB1
DNA topoisomerase 2-binding protein 1 |
3 |
3 |
Small-scale |
0.827 | High |
|
|
RNF8
E3 ubiquitin-protein ligase RNF8 |
2 |
0 |
Small-scale |
0.777 | High |
|
|
RAD50
DNA repair protein RAD50 |
28 |
2 |
Small-scale |
0.766 | High |
|
|
ATM
Serine-protein kinase ATM |
11 |
6 |
Small-scale |
0.755 | High |
|
|
VRK1
Serine/threonine-protein kinase VRK1 |
1 |
0 |
Small-scale |
0.746 | High |
|
|
ATR
Serine/threonine-protein kinase ATR |
5 |
6 |
Small-scale |
0.726 | High |
|
|
H2AX
Histone H2AX |
9 |
0 |
Small-scale |
0.719 | High |
|
|
CTIP
DNA endonuclease RBBP8 |
8 |
0 |
Small-scale |
0.716 | High |
|
|
TERF2
Telomeric repeat-binding factor 2 |
3 |
1 |
Small-scale |
0.676 | High |
|
|
ATRX
Transcriptional regulator ATRX |
4 |
1 |
Small-scale |
0.672 | High |
|
|
RASA2
Ras GTPase-activating protein 2 |
1 |
0 |
High-throughput |
0.656 | High |
|
|
BARD1
BRCA1-associated RING domain protein 1 |
1 |
0 |
Small-scale |
0.656 | High |
|
|
TLK1
Serine/threonine-protein kinase tousled-like 1 |
1 |
1 |
Small-scale |
0.647 | High |
|
|
FACD2
Fanconi anemia group D2 protein |
3 |
0 |
Small-scale |
0.642 | High |
|
|
EP300
Histone acetyltransferase p300 |
2 |
1 |
Small-scale |
0.639 | High |
|
|
TP53B
TP53-binding protein 1 |
2 |
1 |
Small-scale |
0.624 | High |
|
|
RFA1
Replication protein A 70 kDa DNA-binding subunit |
3 |
0 |
Small-scale |
0.619 | High |
|
|
BLM
RecQ-like DNA helicase BLM |
2 |
4 |
Small-scale |
0.619 | High |
|
|
P53
Cellular tumor antigen p53 |
3 |
0 |
High-throughput |
0.619 | High |
|
|
XRCC6
X-ray repair cross-complementing protein 6 |
1 |
1 |
High-throughput |
0.618 | High |
|
|
XRCC5
X-ray repair cross-complementing protein 5 |
1 |
1 |
Small-scale |
0.618 | High |
|
|
CDK9
Cyclin-dependent kinase 9 |
1 |
1 |
Small-scale |
0.618 | High |
|
|
PAXI1
PAX-interacting protein 1 |
1 |
3 |
Small-scale |
0.618 | High |
|
|
ATRIP
ATR-interacting protein |
3 |
0 |
Small-scale |
0.613 | High |
|
|
TCOF
Treacle protein |
1 |
1 |
Small-scale |
0.604 | High |
|
|
BMP1
Bone morphogenetic protein 1 |
2 |
0 |
High-throughput |
0.602 | High |
|
|
LZTS2
Leucine zipper putative tumor suppressor 2 |
2 |
0 |
High-throughput |
0.602 | High |
|
|
SOSB1
SOSS complex subunit B1 |
2 |
0 |
Small-scale |
0.598 | High |
|
|
RAD18
E3 ubiquitin-protein ligase RAD18 |
2 |
0 |
Small-scale |
0.598 | High |
|
|
RPA34
DNA-directed RNA polymerase I subunit RPA34 |
2 |
1 |
Small-scale |
0.594 | High |
|
|
XRCC4
DNA repair protein XRCC4 |
1 |
0 |
Small-scale |
0.589 | High |
|
|
CDK2
Cyclin-dependent kinase 2 |
1 |
0 |
Small-scale |
0.586 | High |
|
|
NOTC1
Neurogenic locus notch homolog protein 1 |
1 |
0 |
Small-scale |
0.586 | High |
|
|
TE2IP
Telomeric repeat-binding factor 2-interacting protein 1 |
1 |
0 |
High-throughput |
0.586 | High |
|
|
RECQ4
ATP-dependent DNA helicase Q4 |
2 |
4 |
Small-scale |
0.584 | High |
|
|
H31
Histone H3.1 |
2 |
1 |
Small-scale |
0.584 | High |
|
|
MDM2
E3 ubiquitin-protein ligase Mdm2 |
2 |
2 |
Small-scale |
0.584 | High |
|
|
WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN |
2 |
4 |
Small-scale |
0.584 | High |
|
|
SLX4
Structure-specific endonuclease subunit SLX4 |
2 |
1 |
Small-scale |
0.584 | High |
|
|
SIR1
NAD-dependent protein deacetylase sirtuin-1 |
1 |
0 |
Small-scale |
0.583 | High |
|
|
PARP1
Poly [ADP-ribose] polymerase 1 |
1 |
2 |
Small-scale |
0.575 | High |
|
|
ESR1
Estrogen receptor |
2 |
5 |
High-throughput |
0.571 | High |
|
|
RAD17
Cell cycle checkpoint protein RAD17 |
1 |
1 |
Small-scale |
0.569 | High |
|
|
RECQ5
ATP-dependent DNA helicase Q5 |
1 |
4 |
Small-scale |
0.561 | High |
|
|
PRKDC
DNA-dependent protein kinase catalytic subunit |
1 |
4 |
Small-scale |
0.561 | High |
|
|
H31T
Histone H3.1t |
1 |
1 |
Small-scale |
0.561 | High |
|
|
PRKN
E3 ubiquitin-protein ligase parkin |
2 |
0 |
Small-scale |
0.559 | High |
|
|
RFA2
Replication protein A 32 kDa subunit |
2 |
0 |
High-throughput |
0.559 | High |
|
|
RFA3
Replication protein A 14 kDa subunit |
2 |
0 |
High-throughput |
0.559 | High |
|
|
E2F1
Transcription factor E2F1 |
2 |
0 |
Small-scale |
0.559 | High |
|
|
SKP2
S-phase kinase-associated protein 2 |
2 |
0 |
Small-scale |
0.559 | High |
|
|
DCR1C
Protein artemis |
2 |
0 |
Small-scale |
0.559 | High |
|
|
FANCJ
Fanconi anemia group J protein |
2 |
0 |
Small-scale |
0.559 | High |
|
|
OFD1
Centriole and centriolar satellite protein OFD1 |
2 |
0 |
High-throughput |
0.547 | High |
|
|
MLH1
DNA mismatch repair protein Mlh1 |
2 |
0 |
Small-scale |
0.547 | High |
|
|
PRKY
Putative serine/threonine-protein kinase PRKY |
1 |
0 |
High-throughput |
0.546 | High |
|
|
RFC1
Replication factor C subunit 1 |
1 |
0 |
Small-scale |
0.546 | High |
|
|
CASC3
Protein CASC3 |
1 |
1 |
High-throughput |
0.541 | High |
|
|
HIF1A
Hypoxia-inducible factor 1-alpha |
1 |
0 |
Small-scale |
0.537 | High |
|
|
UBP7
Ubiquitin carboxyl-terminal hydrolase 7 |
1 |
0 |
Small-scale |
0.537 | High |
|
|
AIM2
Interferon-inducible protein AIM2 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
ERR3
Estrogen-related receptor gamma |
1 |
4 |
High-throughput |
0.536 | High |
|
|
H2B2E
Histone H2B type 2-E |
1 |
1 |
High-throughput |
0.536 | High |
|
|
IFIX
Pyrin and HIN domain-containing protein 1 |
1 |
1 |
High-throughput |
0.536 | High |
|
|
SNAI1
Zinc finger protein SNAI1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
ARY2
Arylamine N-acetyltransferase 2 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
PKHA4
Pleckstrin homology domain-containing family A member 4 |
1 |
0 |
High-throughput |
0.517 | High |
|
|
HMGB1
High mobility group protein B1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
FGF12
Fibroblast growth factor 12 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
SNW1
SNW domain-containing protein 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
NUMA1
Nuclear mitotic apparatus protein 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
RAB43
Ras-related protein Rab-43 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
CDC5L
Cell division cycle 5-like protein |
1 |
0 |
High-throughput |
0.513 | High |
|
|
CBX8
Chromobox protein homolog 8 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
UB2D1
Ubiquitin-conjugating enzyme E2 D1 |
1 |
3 |
Small-scale |
0.501 | High |
|
|
UBE2N
Ubiquitin-conjugating enzyme E2 N |
1 |
2 |
Small-scale |
0.501 | High |
|
|
CCNE1
G1/S-specific cyclin-E1 |
1 |
0 |
Small-scale |
0.493 | High |
|
|
PPIA
Peptidyl-prolyl cis-trans isomerase A |
1 |
0 |
High-throughput |
0.493 | High |
|
|
TERF1
Telomeric repeat-binding factor 1 |
1 |
1 |
Small-scale |
0.481 | High |
|
|
NUCL
Nucleolin |
1 |
0 |
Small-scale |
0.480 | High |
|
|
SUMO2
Small ubiquitin-related modifier 2 |
1 |
0 |
High-throughput |
0.480 | High |
|
|
RAD51
DNA repair protein RAD51 homolog 1 |
1 |
0 |
Small-scale |
0.480 | High |
|
|
RPA1
DNA-directed RNA polymerase I subunit RPA1 |
1 |
0 |
Small-scale |
0.479 | High |
|
|
RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B |
1 |
0 |
Small-scale |
0.479 | High |
|
|
RPA2
DNA-directed RNA polymerase I subunit RPA2 |
1 |
0 |
Small-scale |
0.479 | High |
|
|
ANM5
Protein arginine N-methyltransferase 5 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MDM4
Protein Mdm4 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
RGS20
Regulator of G-protein signaling 20 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
STAU1
Double-stranded RNA-binding protein Staufen homolog 1 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
GCR
Glucocorticoid receptor |
1 |
4 |
High-throughput |
0.479 | High |
|
|
H2B1B
Histone H2B type 1-B |
1 |
1 |
High-throughput |
0.479 | High |
|
|
BMI1
Polycomb complex protein BMI-1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
PPARG
Peroxisome proliferator-activated receptor gamma |
1 |
5 |
Small-scale |
0.479 | High |
|
|
HNF4A
Hepatocyte nuclear factor 4-alpha |
1 |
3 |
High-throughput |
0.479 | High |
|
|
PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform |
1 |
3 |
Small-scale |
0.479 | High |
|
|
MTOR
Serine/threonine-protein kinase mTOR |
1 |
4 |
Small-scale |
0.479 | High |
|
|
UBE2A
Ubiquitin-conjugating enzyme E2 A |
1 |
2 |
Small-scale |
0.479 | High |
|
|
UBE2B
Ubiquitin-conjugating enzyme E2 B |
1 |
2 |
Small-scale |
0.479 | High |
|
|
RED1
Double-stranded RNA-specific editase 1 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
DDX1
ATP-dependent RNA helicase DDX1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ESR2
Estrogen receptor beta |
1 |
4 |
High-throughput |
0.479 | High |
|
|
ANM1
Protein arginine N-methyltransferase 1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme |
1 |
2 |
High-throughput |
0.479 | High |
|
|
EYA2
Protein phosphatase EYA2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MEN1
Menin |
1 |
0 |
High-throughput |
0.458 | High |
|
|
IPO5
Importin-5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
BRD4
Bromodomain-containing protein 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
UBP2
Ubiquitin carboxyl-terminal hydrolase 2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
WDHD1
WD repeat and HMG-box DNA-binding protein 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
UBR5
E3 ubiquitin-protein ligase UBR5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PROF1
Profilin-1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
HS90A
Heat shock protein HSP 90-alpha |
1 |
0 |
Small-scale |
0.458 | High |
|
|
GSTP1
Glutathione S-transferase P |
1 |
0 |
Small-scale |
0.458 | High |
|
|
EF2
Elongation factor 2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TCTP
Translationally-controlled tumor protein |
1 |
0 |
High-throughput |
0.458 | High |
|
|
ATF2
Cyclic AMP-dependent transcription factor ATF-2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
H12
Histone H1.2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
DDX5
Probable ATP-dependent RNA helicase DDX5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
NELFE
Negative elongation factor E |
1 |
0 |
High-throughput |
0.458 | High |
|
|
TBG1
Tubulin gamma-1 chain |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PML
Protein PML |
1 |
0 |
High-throughput |
0.458 | High |
|
|
HSP74
Heat shock 70 kDa protein 4 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
GATA4
Transcription factor GATA-4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
DNLI3
DNA ligase 3 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TERA
Transitional endoplasmic reticulum ATPase |
1 |
0 |
Small-scale |
0.458 | High |
|
|
H4
Histone H4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
DYL1
Dynein light chain 1, cytoplasmic |
1 |
0 |
Small-scale |
0.458 | High |
|
|
DYLT1
Dynein light chain Tctex-type 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
PO5F1
POU domain, class 5, transcription factor 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
ERCC6
DNA excision repair protein ERCC-6 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TF65
Transcription factor p65 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
SUH
Recombining binding protein suppressor of hairless |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PSMD2
26S proteasome non-ATPase regulatory subunit 2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
SMC1A
Structural maintenance of chromosomes protein 1A |
1 |
0 |
Small-scale |
0.458 | High |
|
|
RICTR
Rapamycin-insensitive companion of mTOR |
1 |
0 |
Small-scale |
0.458 | High |
|
|
MOB2
MOB kinase activator 2 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
DPPA4
Developmental pluripotency-associated protein 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
PARPT
Protein mono-ADP-ribosyltransferase TIPARP |
1 |
0 |
High-throughput |
0.458 | High |
|
|
NAA40
N-alpha-acetyltransferase 40 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
SMC5
Structural maintenance of chromosomes protein 5 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
RN169
E3 ubiquitin-protein ligase RNF169 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
KAT5
Histone acetyltransferase KAT5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PELI1
E3 ubiquitin-protein ligase pellino homolog 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
BICD1
Protein bicaudal D homolog 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
SIN1
Target of rapamycin complex 2 subunit MAPKAP1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
RN126
E3 ubiquitin-protein ligase RNF126 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
CYREN
Cell cycle regulator of non-homologous end joining |
1 |
0 |
Small-scale |
0.458 | High |
|
|
WWTR1
WW domain-containing transcription regulator protein 1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
NANOG
Homeobox protein NANOG |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MED4
Mediator of RNA polymerase II transcription subunit 4 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
MCM9
DNA helicase MCM9 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TLS1
Splicing factor C9orf78 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
HDAC6
Protein deacetylase HDAC6 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
ZRAN1
Ubiquitin thioesterase ZRANB1 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
BRPF3
Bromodomain and PHD finger-containing protein 3 |
1 |
0 |
High-throughput |
0.458 | High |
|
|
EXO1
Exonuclease 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
MSH2
DNA mismatch repair protein Msh2 |
1 |
1 |
Small-scale |
0.445 | High |
|
|
MSH6
DNA mismatch repair protein Msh6 |
1 |
1 |
Small-scale |
0.445 | High |
|
|
HOOK3
Protein Hook homolog 3 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
PHRF1
PHD and RING finger domain-containing protein 1 |
1 |
2 |
Small-scale |
0.437 | High |
|
|
HOOK1
Protein Hook homolog 1 |
1 |
1 |
High-throughput |
0.437 | High |
|
|
DAXX
Death domain-associated protein 6 |
1 |
0 |
Small-scale |
0.426 | High |
|
|
CHK2
Serine/threonine-protein kinase Chk2 |
1 |
0 |
Small-scale |
0.414 | High |
|
|
B3KSW4
Regulator of G protein signaling 20 |
1 |
1 |
High-throughput |
0.407 | High |
|
|
CEL2B
Chymotrypsin-like elastase family member 2B |
3 |
0 |
High-throughput |
0.347 | High |
|
|
F219A
Protein FAM219A |
3 |
0 |
High-throughput |
0.347 | High |
|
|
CD6
T-cell differentiation antigen CD6 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
CF161
Cilia- and flagella-associated protein 161 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
TCPQM
T-complex protein 1 subunit theta-like 2 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
DPP4
Dipeptidyl peptidase 4 |
1 |
0 |
High-throughput |
0.269 | Low |
|
|
CATB
Cathepsin B |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
TRI29
Tripartite motif-containing protein 29 |
1 |
0 |
Small-scale |
0.249 | Low |
|
|
TRI67
Tripartite motif-containing protein 67 |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
DNJ5G
DnaJ homolog subfamily C member 5G |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
DJC30
DnaJ homolog subfamily C member 30, mitochondrial |
1 |
0 |
High-throughput |
0.249 | Low |
|
|
S35F4
Solute carrier family 35 member F4 |
1 |
0 |
High-throughput |
0.232 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
