HitPredict

Interactor 1: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Interactor 2: BAZ2B (Q9UIF8)
Bromodomain adjacent to zinc finger domain protein 2B (hWALp4)
Gene: BAZ2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071664
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1834 Hs			1 2168
+	Hs
		1222642 SLX4_HUMAN (1-1834): 0: 1486: 100.00		TRI33_HUMAN (1287-2167): 3.27e-62: 236: 12.60
+	Hs
		170418 SLX4_HUMAN (1-1834): 0: 1486: 100.00		TIF1A_HUMAN (1287-2167): 5.94e-54: 209: 13.25
+	Hs
		1222496 SLX4_HUMAN (1-1834): 0: 1486: 100.00		CBP_HUMAN (1400-2166): 3.89e-51: 202: 10.39
+	Hs
		1154050 SLX4_HUMAN (1-1834): 0: 1486: 100.00		NIPBL_HUMAN (195-1054): 4.22e-42: 173: 12.50
+	Hs
		631499 SLX4_HUMAN (1-1834): 0: 1486: 100.00		BRD2_HUMAN (2051-2167): 1.05e-25: 118: 28.57
+	Hs
		801452 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		BAZ2A_HUMAN (514-2166): 7.6e-150: 515: 30.35
+	Dm
		113976 M9PB30_DROME (1116-1784): 2.28e-27: 124: 8.45		M9PB30_DROME (7-1947): 1.11e-122: 437: 9.12
+	Mm
		101463 F8VPR5_MOUSE (884-1700): 1.05e-28: 128: 9.83		TRI33_MOUSE (1287-2167): 1.31e-59: 228: 12.39
+	Mm
		70879 F8VPR5_MOUSE (884-1700): 1.05e-28: 128: 9.83		EP300_MOUSE (1411-2166): 1.27e-53: 210: 10.61
+	Hs
		1057027 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		TRI33_HUMAN (1287-2167): 3.27e-62: 236: 12.60
+	Hs
		554303 MUC1_HUMAN (1127-1735): 4.53e-16: 87: 11.22		EP300_HUMAN (1411-2166): 1.78e-52: 207: 10.34
+	Mm
		101468 F8VPR5_MOUSE (884-1700): 1.05e-28: 128: 9.83		KAT2A_MOUSE (2056-2163): 1.49e-37: 155: 30.56
+	Hs
		801197 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		NIPBL_HUMAN (195-1054): 4.22e-42: 173: 12.50
+	Hs
		998710 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		EP300_HUMAN (1411-2166): 1.78e-52: 207: 10.34
+	Hs
		1056910 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		CBP_HUMAN (1400-2166): 3.89e-51: 202: 10.39
+	Hs
		170437 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		TIF1A_HUMAN (1287-2167): 5.94e-54: 209: 13.25
+	Mm
		101467 F8VPR5_MOUSE (884-1700): 1.05e-28: 128: 9.83		KAT2B_MOUSE (2049-2163): 6.31e-34: 144: 30.44
+	Hs
		152608 KI67_HUMAN (889-1833): 3.44e-23: 110: 10.79		KMT2D_HUMAN (1848-2095): 1.1e-16: 89.5: 14.92
+	Hs
		631425 MDC1_HUMAN (801-1763): 7.3e-12: 73.2: 9.54		BRD2_HUMAN (2051-2167): 1.05e-25: 118: 28.57
+	Hs
		152675 CBP_HUMAN (885-1778): 4.86e-09: 64: 9.57		KMT2D_HUMAN (1848-2095): 1.1e-16: 89.5: 14.92