HitPredict

Interactor 1: MKX (Q8IYA7)
Homeobox protein Mohawk
Gene: MKX

Interactor 2: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 352 Hs			1 514
+	Hs
		245617 MKX_HUMAN (1-352): 3.9e-114: 337: 100.00		TBL1X_HUMAN (1-514): 1.2e-150: 444: 86.34
+	Mm
		936377 TGIF1_MOUSE (63-128): 2.27e-25: 104: 40.91		FBXW7_MOUSE (39-423): 1.26e-69: 237: 15.64
+	Mm
		1207862 TGIF2_MOUSE (63-128): 2.99e-23: 98.3: 37.88		FBXW7_MOUSE (39-423): 1.26e-69: 237: 15.64
+	Hs
		1281375 TGIF2_HUMAN (63-128): 2.7e-23: 98.3: 37.88		FBXW7_HUMAN (39-423): 4.25e-69: 236: 15.64