Protein: FAT1
Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]

Gene: FAT1
Organism: Homo sapiens
Interactions: 98
UniProt ID: Q14517

Gene Ontology (top 5):
GO:0002088 - lens development in camera-type eye
GO:0003382 - epithelial cell morphogenesis
GO:0003412 - establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis
GO:0005509 - calcium ion binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1055023

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

13

High-throughput

0.811

High

305216

NXPH2
Neurexophilin-2

3

9

High-throughput

0.770

High

59826

PRS37
Probable inactive serine protease 37

1

11

High-throughput

0.691

High

621366

CMA1
Chymase

1

8

High-throughput

0.691

High

685240

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

13

High-throughput

0.691

High

411385

INSR
Insulin receptor

1

4

High-throughput

0.646

High

900469

RHOA
Transforming protein RhoA

3

12

High-throughput

0.633

High

925280

RAC1
Ras-related C3 botulinum toxin substrate 1

3

12

High-throughput

0.633

High

350967

PDGFB
Platelet-derived growth factor subunit B

2

3

High-throughput

0.628

High

1055022

DKKL1
Dickkopf-like protein 1

2

6

High-throughput

0.628

High

434195

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

2

High-throughput

0.618

High

1055016

TMPS4
Transmembrane protease serine 4

1

4

High-throughput

0.618

High

1055020

KLK11
Kallikrein-11

1

5

High-throughput

0.618

High

1055006

CB048
Putative uncharacterized protein C2orf48

3

2

High-throughput

0.609

High

1055009

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

2

0

High-throughput

0.602

High

1054998

LIPH
Lipase member H

2

0

High-throughput

0.585

High

1054993

IFNE
Interferon epsilon

2

2

High-throughput

0.574

High

1055000

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

2

High-throughput

0.574

High

498278

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

2

High-throughput

0.571

High

584248

ELK1
ETS domain-containing protein Elk-1

2

1

High-throughput

0.571

High

805418

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

4

High-throughput

0.571

High

972196

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

4

High-throughput

0.571

High

983835

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.571

High

1031662

GRB10
Growth factor receptor-bound protein 10

2

7

High-throughput

0.571

High

1054991

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

1

Small-scale

0.552

High

1055014

XAGE1
X antigen family member 1

2

6

High-throughput

0.549

High

1055017

HOME3
Homer protein homolog 3

1

5

Small-scale

0.536

High

63921

C2C4B
C2 calcium-dependent domain-containing protein 4B

1

6

High-throughput

0.536

High

328263

BY55
CD160 antigen

1

6

High-throughput

0.536

High

341606

RENI
Renin

1

2

High-throughput

0.536

High

578225

LAG3
Lymphocyte activation gene 3 protein

1

4

High-throughput

0.536

High

1030711

SLAF1
Signaling lymphocytic activation molecule

1

17

High-throughput

0.536

High

1033466

ILK
Integrin-linked protein kinase

1

2

High-throughput

0.536

High

1054983

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.536

High

1054984

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.536

High

1054995

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.536

High

1055003

SPSB4
SPRY domain-containing SOCS box protein 4

1

15

High-throughput

0.536

High

1055024

CCL26
C-C motif chemokine 26

1

5

High-throughput

0.536

High

1055025

DTX4
E3 ubiquitin-protein ligase DTX4

1

2

High-throughput

0.536

High

1055026

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.536

High

1054988

SUSD4
Sushi domain-containing protein 4

1

0

High-throughput

0.517

High

513416

FGF3
Fibroblast growth factor 3

1

0

High-throughput

0.513

High

1054989

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.513

High

475758

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

833737

CLK1
Dual specificity protein kinase CLK1

1

5

High-throughput

0.501

High

840473

VASP
Vasodilator-stimulated phosphoprotein

1

5

Small-scale

0.501

High

1054994

HOME1
Homer protein homolog 1

1

5

Small-scale

0.501

High

1054996

ENAH
Protein enabled homolog

1

8

Small-scale

0.501

High

435095

SP1
Transcription factor Sp1

1

2

High-throughput

0.500

High

1054997

DCNP1
Dendritic cell nuclear protein 1

1

6

High-throughput

0.489

High

1055002

UCN3
Urocortin-3

1

2

High-throughput

0.489

High

1055004

LCFC1
Sperm-egg fusion protein LLCFC1

1

3

High-throughput

0.489

High

298980

SRBS2
Sorbin and SH3 domain-containing protein 2

1

6

Small-scale

0.481

High

1049024

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.481

High

164378

TRI66
Tripartite motif-containing protein 66

1

3

High-throughput

0.479

High

205390

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

217479

AIRE
Autoimmune regulator

1

3

High-throughput

0.479

High

348665

RASN
GTPase NRas

1

10

High-throughput

0.479

High

436302

RHOC
Rho-related GTP-binding protein RhoC

1

12

High-throughput

0.479

High

441504

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.479

High

545377

RAC2
Ras-related C3 botulinum toxin substrate 2

1

11

High-throughput

0.479

High

564529

RHOQ
Rho-related GTP-binding protein RhoQ

1

14

High-throughput

0.479

High

892373

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

894007

CDC42
Cell division control protein 42 homolog

1

13

High-throughput

0.479

High

915678

RHOB
Rho-related GTP-binding protein RhoB

1

13

High-throughput

0.479

High

950997

RHOG
Rho-related GTP-binding protein RhoG

1

11

High-throughput

0.479

High

1041571

CUL3
Cullin-3

1

2

High-throughput

0.479

High

1054048

GRB7
Growth factor receptor-bound protein 7

1

8

Small-scale

0.479

High

1055012

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.479

High

1055013

RHOF
Rho-related GTP-binding protein RhoF

1

15

High-throughput

0.479

High

1055018

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

1055028

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.479

High

1054992

NOXA1
NADPH oxidase activator 1

1

0

Small-scale

0.460

High

1055011

TRAF4
TNF receptor-associated factor 4

1

0

Small-scale

0.460

High

718501

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

770287

TACT
T-cell surface protein tactile

1

0

High-throughput

0.458

High

921566

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

1029228

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.458

High

1054986

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1055001

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

Small-scale

0.458

High

1055019

HDAC6
Histone deacetylase 6

1

0

Small-scale

0.458

High

1055021

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1055027

NUB1
NEDD8 ultimate buster 1

1

0

Small-scale

0.458

High

529117

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

949782

CBX1
Chromobox protein homolog 1

1

9

Small-scale

0.445

High

834226

VEGFB
Vascular endothelial growth factor B

1

3

High-throughput

0.437

High

1055015

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.426

High

1054990

BRNP3
BMP/retinoic acid-inducible neural-specific protein 3

2

0

High-throughput

0.328

High

1054987

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

1055007

IL17F
Interleukin-17F

1

0

High-throughput

0.279

Low

1055010

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

371087

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

0

Small-scale

0.251

Low

550306

IGLL1
Immunoglobulin lambda-like polypeptide 1

1

0

Small-scale

0.251

Low

100762

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1054985

TAZ
Tafazzin

1

0

High-throughput

0.249

Low

1054999

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.249

Low

1055005

CALR3
Calreticulin-3

1

0

High-throughput

0.249

Low

1055008

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024