Protein: Q86WV8
TSC complex subunit 1 (Tuberous sclerosis 1)

Gene: Q86WV8, TSC1
Organism: Homo sapiens
Interactions: 126
UniProt ID: Q86WV8

Gene Ontology (top 5):

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1292915

MYLIP
E3 ubiquitin-protein ligase MYLIP

2

7

High-throughput

0.558

High

1292927

SPAG8
Sperm-associated antigen 8

2

1

High-throughput

0.558

High

63225

VP37C
Vacuolar protein sorting-associated protein 37C

1

2

High-throughput

0.470

High

71126

VGLL3
Transcription cofactor vestigial-like protein 3

1

1

High-throughput

0.470

High

109451

G5E9A7
DM1 locus, WD repeat containing

1

2

High-throughput

0.470

High

116865

I6L9F6
NEFL protein

1

3

High-throughput

0.470

High

140338

SDCB1
Syntenin-1

1

3

High-throughput

0.470

High

167309

KLF11
Krueppel-like factor 11

1

1

High-throughput

0.470

High

208862

ZBT24
Zinc finger and BTB domain-containing protein 24

1

2

High-throughput

0.470

High

220267

FRS3
Fibroblast growth factor receptor substrate 3

1

2

High-throughput

0.470

High

221040

HAIR
Lysine-specific demethylase hairless

1

1

High-throughput

0.470

High

246020

KIF1B
Kinesin-like protein KIF1B

1

3

High-throughput

0.470

High

288111

FOXH1
Forkhead box protein H1

1

3

High-throughput

0.470

High

330228

VENTX
Homeobox protein VENTX

1

3

High-throughput

0.470

High

347790

BAG3
BAG family molecular chaperone regulator 3

1

1

High-throughput

0.470

High

350478

GPAN1
G patch domain and ankyrin repeat-containing protein 1

1

3

High-throughput

0.470

High

351447

TBX6
T-box transcription factor TBX6

1

1

High-throughput

0.470

High

354059

HAND1
Heart- and neural crest derivatives-expressed protein 1

1

1

High-throughput

0.470

High

478329

HXC4
Homeobox protein Hox-C4

1

2

High-throughput

0.470

High

681859

RBTN2
Rhombotin-2

1

3

High-throughput

0.470

High

715924

AQP1
Aquaporin-1

1

1

High-throughput

0.470

High

725083

HXC8
Homeobox protein Hox-C8

1

2

High-throughput

0.470

High

750440

CSTF2
Cleavage stimulation factor subunit 2

1

1

High-throughput

0.470

High

873165

RXRG
Retinoic acid receptor RXR-gamma

1

3

High-throughput

0.470

High

907159

SUOX
Sulfite oxidase, mitochondrial

1

1

High-throughput

0.470

High

927394

ATX1
Ataxin-1

1

1

High-throughput

0.470

High

1005609

PITX1
Pituitary homeobox 1

1

2

High-throughput

0.470

High

1007949

PO6F2
POU domain, class 6, transcription factor 2

1

1

High-throughput

0.470

High

1044672

ARI5A
AT-rich interactive domain-containing protein 5A

1

1

High-throughput

0.470

High

1061758

TLE5
TLE family member 5

1

1

High-throughput

0.470

High

1092174

NFX1
Transcriptional repressor NF-X1

1

3

High-throughput

0.470

High

1116672

RIN1
Ras and Rab interactor 1

1

3

High-throughput

0.470

High

1120677

VEZF1
Vascular endothelial zinc finger 1

1

4

High-throughput

0.470

High

1134829

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

3

High-throughput

0.470

High

1155358

RB11B
Ras-related protein Rab-11B

1

4

High-throughput

0.470

High

1156028

ZIC1
Zinc finger protein ZIC 1

1

3

High-throughput

0.470

High

1168946

LONF2
LON peptidase N-terminal domain and RING finger protein 2

1

1

High-throughput

0.470

High

1187646

T10IP
Testis-specific protein 10-interacting protein

1

1

High-throughput

0.470

High

1215321

DCAF8
DDB1- and CUL4-associated factor 8

1

1

High-throughput

0.470

High

1224693

TSH3
Teashirt homolog 3

1

1

High-throughput

0.470

High

1229357

LHX8
LIM/homeobox protein Lhx8

1

1

High-throughput

0.470

High

1239706

PPR18
Phostensin

1

1

High-throughput

0.470

High

1241213

CA094
Uncharacterized protein C1orf94

1

1

High-throughput

0.470

High

1244924

FOXR1
Forkhead box protein R1

1

1

High-throughput

0.470

High

1251015

ASCL4
Achaete-scute homolog 4

1

1

High-throughput

0.470

High

1252719

ZFP2
Zinc finger protein ZFP2

1

1

High-throughput

0.470

High

1253031

RUFY4
RUN and FYVE domain-containing protein 4

1

1

High-throughput

0.470

High

1253624

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.470

High

1271959

ZN765
Zinc finger protein 765

1

1

High-throughput

0.470

High

1277102

SAMD7
Sterile alpha motif domain-containing protein 7

1

4

High-throughput

0.470

High

1277172

POGZ
Pogo transposable element with ZNF domain

1

2

High-throughput

0.470

High

1279446

SAXO4
Stabilizer of axonemal microtubules 4

1

1

High-throughput

0.470

High

1279605

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

1280257

AP2D
Transcription factor AP-2-delta

1

1

High-throughput

0.470

High

1287090

PATL1
Protein PAT1 homolog 1

1

2

High-throughput

0.470

High

1290356

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.470

High

1292904

ZN444
Zinc finger protein 444

1

1

High-throughput

0.470

High

1292905

ZN366
Zinc finger protein 366

1

1

High-throughput

0.470

High

1292906

GMCL2
Germ cell-less protein-like 2

1

2

High-throughput

0.470

High

1292907

VP37A
Vacuolar protein sorting-associated protein 37A

1

2

High-throughput

0.470

High

1292908

ZN417
Zinc finger protein 417

1

4

High-throughput

0.470

High

1292910

LNX1
E3 ubiquitin-protein ligase LNX

1

3

High-throughput

0.470

High

1292911

MYOZ3
Myozenin-3

1

1

High-throughput

0.470

High

1292912

F222B
Protein FAM222B

1

1

High-throughput

0.470

High

1292916

SHC3
SHC-transforming protein 3

1

1

High-throughput

0.470

High

1292917

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.470

High

1292919

LENG1
Leukocyte receptor cluster member 1

1

1

High-throughput

0.470

High

1292922

CC120
Coiled-coil domain-containing protein 120

1

1

High-throughput

0.470

High

1292925

SAM11
Sterile alpha motif domain-containing protein 11

1

4

High-throughput

0.470

High

1292926

ZN587
Zinc finger protein 587

1

3

High-throughput

0.470

High

1292928

F110A
Protein FAM110A

1

1

High-throughput

0.470

High

1292930

GLIS2
Zinc finger protein GLIS2

1

4

High-throughput

0.470

High

1292931

ENKD1
Enkurin domain-containing protein 1

1

1

High-throughput

0.470

High

1292932

SMG9
Nonsense-mediated mRNA decay factor SMG9

1

1

High-throughput

0.470

High

1292934

LHX5
LIM/homeobox protein Lhx5

1

1

High-throughput

0.470

High

1292935

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

5

High-throughput

0.470

High

1292936

TF7L2
Transcription factor 7-like 2

1

2

High-throughput

0.470

High

1292937

DMRT3
Doublesex- and mab-3-related transcription factor 3

1

1

High-throughput

0.470

High

1292938

PAR11
Protein mono-ADP-ribosyltransferase PARP11

1

1

High-throughput

0.470

High

1292939

CCL28
C-C motif chemokine 28

1

1

High-throughput

0.470

High

1292943

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

1

High-throughput

0.470

High

1292944

MAGC2
Melanoma-associated antigen C2

1

2

High-throughput

0.470

High

1292946

KLH20
Kelch-like protein 20

1

1

High-throughput

0.470

High

1292949

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.470

High

60682

A2RU56
LOC401296 protein

1

0

High-throughput

0.268

Low

137245

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.268

Low

159987

IDLC
Axonemal dynein light intermediate polypeptide 1

1

0

High-throughput

0.268

Low

301532

WFS1
Wolframin

1

0

High-throughput

0.268

Low

341438

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.268

Low

415690

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.268

Low

642571

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.268

Low

686678

ASPX
Acrosomal protein SP-10

1

0

High-throughput

0.268

Low

772175

MSX2
Homeobox protein MSX-2

1

0

High-throughput

0.268

Low

818748

CAPG
Macrophage-capping protein

1

0

High-throughput

0.268

Low

856782

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.268

Low

867710

RGR
RPE-retinal G protein-coupled receptor

1

0

High-throughput

0.268

Low

954525

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.268

Low

1128596

ZN345
Zinc finger protein 345

1

0

High-throughput

0.268

Low

1159447

BAK
Bcl-2 homologous antagonist/killer

1

0

High-throughput

0.268

Low

1165411

FA98C
Protein FAM98C

1

0

High-throughput

0.268

Low

1208146

CD158
Coiled-coil domain-containing protein 158

1

0

High-throughput

0.268

Low

1232967

OTU7B
OTU domain-containing protein 7B

1

0

High-throughput

0.268

Low

1258126

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

0

High-throughput

0.268

Low

1259209

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

1

0

High-throughput

0.268

Low

1292068

SPA24
Spermatogenesis-associated protein 24

1

0

High-throughput

0.268

Low

1292721

TRI69
E3 ubiquitin-protein ligase TRIM69

1

0

High-throughput

0.268

Low

1292900

CRLF3
Cytokine receptor-like factor 3

1

0

High-throughput

0.268

Low

1292901

HID1
Protein HID1

1

0

High-throughput

0.268

Low

1292902

SLN12
Ribonuclease SLFN12

1

0

High-throughput

0.268

Low

1292903

TMM61
Transmembrane protein 61

1

0

High-throughput

0.268

Low

1292909

CX038
Uncharacterized protein CXorf38

1

0

High-throughput

0.268

Low

1292913

RN138
E3 ubiquitin-protein ligase RNF138

1

0

High-throughput

0.268

Low

1292914

ATLA1
Atlastin-1

1

0

High-throughput

0.268

Low

1292918

COQA1
Collagen alpha-1(XXVI) chain

1

0

High-throughput

0.268

Low

1292920

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.268

Low

1292921

OTUB1
Ubiquitin thioesterase OTUB1

1

0

High-throughput

0.268

Low

1292923

CH048
Uncharacterized protein C8orf48

1

0

High-throughput

0.268

Low

1292924

ZN488
Zinc finger protein 488

1

0

High-throughput

0.268

Low

1292929

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1292933

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.268

Low

1292940

RFOX1
RNA binding protein fox-1 homolog 1

1

0

High-throughput

0.268

Low

1292941

GPT2L
G patch domain-containing protein 2-like

1

0

High-throughput

0.268

Low

1292942

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.268

Low

1292945

CHIP
E3 ubiquitin-protein ligase CHIP

1

0

High-throughput

0.268

Low

1292947

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

1292948

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025