HitPredict

Interactor 1: BMR1B (O00238)
Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)
Gene: BMPR1B

Interactor 2: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 7791754, 10712517
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~Activin_recp, PK_Tyr_Ser-Thr~Pkinase, Pkinase~TGF_beta_GS
Common GO terms GO:0001649 - osteoblast differentiation
GO:0002063 - chondrocyte development
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0010628 - positive regulation of gene expression
and 17 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 502
Hs

1 1038
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024