HitPredict

Interactor 1: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19270156
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2048 Hs			1 605
+	Hs
		1223020 FANCM_HUMAN (1-2048): 0: 1666: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1102073 ERC6L_HUMAN (1-1232): 1.73e-116: 404: 11.51		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1336307 CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		321921 RIGI_HUMAN (52-637): 3.28e-125: 421: 20.09		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1254435 CHD6_HUMAN (42-1218): 5.58e-109: 391: 12.33		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		658714 SMCA1_HUMAN (4-1033): 8.64e-110: 379: 13.04		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		571638 DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		134256 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1059779 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1018714 CHD3_HUMAN (29-1087): 1.86e-103: 372: 13.16		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		134246 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		197011 CHD3_HUMAN (29-1087): 1.86e-103: 372: 13.16		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		209485 CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		903535 CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		903234 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		197020 CHD4_HUMAN (41-1065): 7.17e-95: 344: 11.88		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		1309165 CHD8_HUMAN (42-1069): 6.88e-95: 345: 12.12		TBL1Y_HUMAN (501-605): 2.08e-14: 78.1: 20.00
+	Hs
		134154 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		571382 DDX5_HUMAN (13-334): 4.25e-20: 98.9: 16.10		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		133956 DDX3X_HUMAN (19-341): 3.67e-19: 96.2: 15.70		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33