HitPredict

Interactor 1: FXR1 (Q61584)
RNA-binding protein FXR1 (FXR1P) (mFxr1p)
Gene: FXR1

Interactor 2: Q8BPK8 (Q8BPK8)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein)
Gene: Fmr1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Agenet~Agenet, Agenet~KH_9, Agenet~Tudor_FRX1, KH_1~KH_1, KH_9~Tudor_FRX1
Common GO terms	GO:0003729 - mRNA binding GO:0005737 - cytoplasm GO:0098794 - postsynapse
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 677 Mm			1 357
+	Mm
		777902 FXR1_MOUSE (1-677): 0: 1073: 100.00		FMR1_MOUSE (1-357): 0: 654: 100.00
+	Mm
		1223031 FXR1_MOUSE (1-677): 0: 1073: 100.00		Q6P5B5_MOUSE (4-334): 0: 577: 71.60
+	Hs
		899852 FXR1_HUMAN (1-677): 0: 995: 88.33		FMR1_HUMAN (1-357): 0: 649: 97.76
+	Mm
		1223108 FXR1_MOUSE (1-677): 0: 1073: 100.00		FXR2_MOUSE (4-334): 0: 559: 69.49
+	Hs
		899786 FXR1_HUMAN (1-677): 0: 995: 88.33		FXR1_HUMAN (1-334): 0: 592: 73.95
+	Hs
		899787 FXR1_HUMAN (1-677): 0: 995: 88.33		FXR2_HUMAN (4-334): 0: 579: 71.90
+	Hs
		900025 FXR1_HUMAN (1-677): 0: 995: 88.33		Q8IXW7_HUMAN (1-294): 0: 546: 98.64
+	Mm
		1242717 Q6P5B5_MOUSE (4-656): 0: 861: 63.81		Q8BPK8_MOUSE (1-357): 0: 650: 100.00
+	Hs
		900288 FXR2_HUMAN (4-656): 0: 851: 64.06		FMR1_HUMAN (1-357): 0: 649: 97.76
+	Mm
		778020 FXR2_MOUSE (4-656): 0: 830: 62.46		FMR1_MOUSE (1-357): 0: 654: 100.00
+	Hs
		900252 FXR2_HUMAN (4-656): 0: 851: 64.06		FXR2_HUMAN (4-334): 0: 579: 71.90
+	Hs
		900408 FXR2_HUMAN (4-656): 0: 851: 64.06		Q8IXW7_HUMAN (1-294): 0: 546: 98.64
+	Dm
		1445514 FMR1_DROME (1-562): 0: 665: 41.03		FMR1_DROME (1-334): 7e-178: 511: 45.93