Interactor 1: FXR1 (P51114)
RNA-binding protein FXR1 (FMR1 autosomal homolog 1) (hFXR1p)
Gene: FXR1

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 26186194, 32296183, 8668200, 29395067, 26949739, 21653829, 7489725, 40437099, 24778252, 24981860, 38177924, unassigned1973, 32525608
Identification Methods affinity chromatography technology, two hybrid, biochemical, proximity labelling technology, pull down, cross-linking study, tandem affinity purification, two hybrid fragment pooling approach, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Agenet~Agenet, Agenet~KH_9, Agenet~Tudor_FRX1, KH_1~KH_1, KH_9~Tudor_FRX1
Common GO terms GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
and 24 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 621
Hs

1 632
+ Mm
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+ Dm

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Last updated: 11Aug2025