Interactor 1: PHS (P61457)
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)
Gene: PCBD1
Interactor 2: PHS (P61457)
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)
Gene: PCBD1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 16189514, 21516116, 32296183, 21047120, unassigned1304, 20211142 |
| Identification Methods | two hybrid, affinity chromatography technology, x-ray crystallography, pull down, two hybrid array, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pterin_4a~Pterin_4a |
| Common GO terms | GO:0003713 - transcription coactivator activity GO:0004505 - phenylalanine 4-monooxygenase activity GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006729 - tetrahydrobiopterin biosynthetic process and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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| + | Hs | |
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| + | Sp | |
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| + | Sc | |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
