HitPredict

Interactor 1: PACE1 (Q8IZE3)
Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3)
Gene: SCYL3

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 742 Hs			1 874
+	Hs
		1224302 PACE1_HUMAN (1-742): 1.18e-176: 525: 100.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		1296197 SCYL1_HUMAN (13-423): 6.24e-115: 367: 27.44		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		1296185 SCYL1_HUMAN (13-423): 6.24e-115: 367: 27.44		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Rn
		923854 SCYL1_RAT (13-423): 3.14e-112: 360: 26.98		AP2B1_RAT (14-871): 0: 591: 12.40
+	Rn
		88765 SCYL1_RAT (13-423): 3.14e-112: 360: 26.98		D3ZUY8_RAT (24-874): 0: 589: 14.74
+	Hs
		302146 KCC2D_HUMAN (5-516): 1.03e-113: 354: 12.43		AP2A2_HUMAN (24-874): 0: 575: 15.97
+	Hs
		925914 SCYL2_HUMAN (14-456): 1.95e-86: 294: 19.37		AP2B1_HUMAN (14-871): 0: 591: 12.40