HitPredict

Interactor 1: NRX2B (P58401)
Neurexin-2-beta (Neurexin II-beta)
Gene: NRXN2

Interactor 2: NLGN1 (Q8N2Q7)
Neuroligin-1
Gene: NLGN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	8576240
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	COesterase~Laminin_G_2
Common GO terms	GO:0005886 - plasma membrane GO:0007158 - neuron cell-cell adhesion GO:0050839 - cell adhesion molecule binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 666 Hs			1 863
+	Hs
		1324506 NRX3A_HUMAN (85-666): 0: 837: 55.61		NLGN1_HUMAN (1-863): 0: 1305: 100.00
+	Hs
		1453099 NRX3A_HUMAN (85-666): 0: 837: 55.61		NLGN3_HUMAN (33-863): 0: 1101: 70.45
+	Rn
		1224301 NRX2A_RAT (86-666): 0: 1018: 97.94		NLGN2_RAT (53-863): 0: 913: 62.16
+	Hs
		946294 NRX2B_HUMAN (13-666): 0: 943: 100.00		NLGN2_HUMAN (53-863): 0: 901: 61.71
+	Hs
		1339618 NRX3A_HUMAN (85-666): 0: 837: 55.61		NLGN2_HUMAN (53-863): 0: 901: 61.71
+	Hs
		946278 NRX1B_HUMAN (566-666): 1.33e-44: 168: 83.33		NLGN1_HUMAN (1-863): 0: 1305: 100.00
+	Rn
		1224272 NRX1B_RAT (566-666): 5.03e-47: 174: 83.33		NLGN1_RAT (1-863): 0: 1255: 95.94
+	Rn
		1224308 NRX1A_RAT (566-666): 2.62e-45: 176: 83.33		NLGN3_RAT (33-863): 0: 1100: 70.69
+	Hs
		946282 NRX1B_HUMAN (566-666): 1.33e-44: 168: 83.33		NLGN3_HUMAN (33-863): 0: 1101: 70.45
+	Rn
		1224300 NRX1B_RAT (566-666): 5.03e-47: 174: 83.33		NLGN2_RAT (53-863): 0: 913: 62.16
+	Hs
		946279 NRX1B_HUMAN (566-666): 1.33e-44: 168: 83.33		NLGN2_HUMAN (53-863): 0: 901: 61.71
+	Dm
		1185779 NRX1_DROME (86-286): 2.13e-13: 76: 19.80		Q9VIC7_DROME (42-661): 1.45e-161: 508: 31.44
+	Dm
		1185775 NRX1_DROME (86-286): 2.13e-13: 76: 19.80		Q9NGK5_DROME (55-630): 5.71e-146: 464: 32.29