Interactor 1: MEN1 (O00255)
Menin
Gene: MEN1

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.589

The method score is based on:

Property Details
Experiments 11526476
Identification Methods pull down, affinity chromatography technology, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 610
Hs

1 551
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024