HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: DVL3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	31015422
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DEP~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 716
+	Hs
		159362 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		DVL1_HUMAN (1-716): 1.2e-144: 440: 63.38
+	Hs
		159696 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		DVL2_HUMAN (3-716): 2.28e-126: 394: 64.82
+	Hs
		159389 SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81		DVL1_HUMAN (1-716): 1.2e-144: 440: 63.38
+	Hs
		159333 GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30		DVL1_HUMAN (1-716): 1.2e-144: 440: 63.38
+	Hs
		1150517 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		DIXC1_HUMAN (4-85): 2.07e-29: 126: 38.55
+	Hs
		1090144 A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00		PTN13_HUMAN (65-379): 1.39e-10: 67.2: 13.57
+	Dm
		900646 EBI_DROME (254-478): 1.49e-54: 199: 19.17		DSH_DROME (3-559): 3.14e-95: 309: 45.95
+	Hs
		936283 WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43		AFAD_HUMAN (130-681): 8.93e-46: 178: 15.16
+	Mm
		983630 GBB1_MOUSE (165-516): 2.35e-43: 160: 17.18		DLG4_MOUSE (96-628): 1.46e-52: 195: 14.34
+	Hs
		984090 GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30		PTN13_HUMAN (65-379): 1.39e-10: 67.2: 13.57
+	Mm
		266762 LIS1_MOUSE (99-438): 1.04e-47: 174: 14.72		LNX1_MOUSE (116-368): 2.77e-15: 81.7: 17.11