HitPredict

Interactor 1: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Interactor 2: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	25416956, 32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 450
+	Hs
		300514 KRT34_HUMAN (29-430): 8.4e-153: 440: 62.53		ZN446_HUMAN (1-450): 7.95e-114: 343: 100.00
+	Hs
		300363 KRT34_HUMAN (29-430): 8.4e-153: 440: 62.53		ZNF79_HUMAN (94-448): 4.99e-103: 317: 16.45
+	Hs
		1230324 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		ZSC21_HUMAN (4-448): 2.17e-125: 373: 23.58
+	Hs
		1367987 KRT35_HUMAN (2-427): 1.91e-84: 267: 59.35		ZN446_HUMAN (1-450): 7.95e-114: 343: 100.00
+	Hs
		1200626 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		Q53Z40_HUMAN (1-448): 1.24e-112: 341: 23.36
+	Hs
		892403 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		ZN165_HUMAN (1-448): 1.24e-112: 341: 23.36
+	Hs
		1146190 K1H1_HUMAN (44-425): 1.31e-72: 235: 62.57		ZN446_HUMAN (1-450): 7.95e-114: 343: 100.00
+	Hs
		1208174 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		ZN569_HUMAN (74-218): 7.88e-20: 94.2: 5.33
+	Hs
		1145968 K1H1_HUMAN (44-425): 1.31e-72: 235: 62.57		ZN569_HUMAN (74-218): 7.88e-20: 94.2: 5.33
+	Hs
		326411 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		ZN202_HUMAN (230-329): 6.79e-10: 63.2: 12.75