HitPredict

Interactor 1: H2A2A (Q6FI13)
Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o)
Gene: H2AC18

Interactor 2: MIER1 (Q8N108)
Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1)
Gene: MIER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 130 Hs			1 512
+	Hs
		502430 H2A1_HUMAN (1-130): 5.11e-67: 200: 98.46		MIER1_HUMAN (1-512): 2.65e-159: 464: 100.00
+	Hs
		419079 H2A1B_HUMAN (1-130): 8.1e-67: 199: 96.92		MIER1_HUMAN (1-512): 2.65e-159: 464: 100.00
+	Hs
		1162830 H2A2C_HUMAN (1-128): 2.25e-64: 193: 96.88		MIER1_HUMAN (1-512): 2.65e-159: 464: 100.00
+	Hs
		1322544 H2AJ_HUMAN (1-128): 2.45e-64: 193: 94.53		MIER1_HUMAN (1-512): 2.65e-159: 464: 100.00
+	Hs
		591728 H2AX_HUMAN (1-130): 3.31e-63: 190: 88.81		MIER1_HUMAN (1-512): 2.65e-159: 464: 100.00
+	Hs
		502408 H2A1_HUMAN (1-130): 5.11e-67: 200: 98.46		MIER3_HUMAN (1-488): 9.02e-132: 395: 46.83
+	Hs
		419050 H2A1B_HUMAN (1-130): 8.1e-67: 199: 96.92		MIER3_HUMAN (1-488): 9.02e-132: 395: 46.83
+	Hs
		1162814 H2A2C_HUMAN (1-128): 2.25e-64: 193: 96.88		MIER3_HUMAN (1-488): 9.02e-132: 395: 46.83
+	Hs
		1277273 H2AJ_HUMAN (1-128): 2.45e-64: 193: 94.53		MIER3_HUMAN (1-488): 9.02e-132: 395: 46.83
+	Hs
		591711 H2AX_HUMAN (1-130): 3.31e-63: 190: 88.81		MIER3_HUMAN (1-488): 9.02e-132: 395: 46.83
+	Hs
		591821 H2AX_HUMAN (1-130): 3.31e-63: 190: 88.81		MTA3_HUMAN (94-483): 1.03e-106: 332: 16.14
+	Hs
		316741 H2AX_HUMAN (1-130): 3.31e-63: 190: 88.81		MTA2_HUMAN (94-501): 7.96e-98: 311: 17.62
+	Hs
		591634 H2AX_HUMAN (1-130): 3.31e-63: 190: 88.81		MTA1_HUMAN (94-507): 2.52e-93: 300: 16.00
+	Hs
		419040 H2A1B_HUMAN (1-130): 8.1e-67: 199: 96.92		MDEAS_HUMAN (94-457): 1.75e-64: 228: 15.67
+	Hs
		591881 H2AX_HUMAN (1-130): 3.31e-63: 190: 88.81		RCOR1_HUMAN (180-512): 8.24e-67: 225: 17.26