Protein: MDEAS
Mitotic deacetylase-associated SANT domain protein (ELM2 and SANT domain-containing protein 1)

Gene: MDEAS, MIDEAS
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q6PJG2

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1109827

HDAC1
Histone deacetylase 1

7

20

High-throughput

0.969

High

1245174

HDAC2
Histone deacetylase 2

5

20

High-throughput

0.930

High

1245179

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

3

2

High-throughput

0.871

High

1158119

MK14
Mitogen-activated protein kinase 14

5

2

High-throughput

0.718

High

629131

CCNA2
Cyclin-A2

4

0

High-throughput

0.670

High

372340

MYC
Myc proto-oncogene protein

3

11

High-throughput

0.633

High

1245177

TREF1
Transcriptional-regulating factor 1

2

14

High-throughput

0.628

High

396348

ESR1
Estrogen receptor

2

20

High-throughput

0.611

High

143061

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

474072

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

520143

ANDR
Androgen receptor

2

20

High-throughput

0.584

High

872449

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.584

High

998455

H31
Histone H3.1

2

20

High-throughput

0.584

High

1087813

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

1133478

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

572033

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.536

High

624081

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

4

High-throughput

0.536

High

667911

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.536

High

907474

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

3

High-throughput

0.536

High

1055928

RAD51
DNA repair protein RAD51 homolog 1

1

1

High-throughput

0.536

High

1123570

ZMYM3
Zinc finger MYM-type protein 3

1

7

High-throughput

0.536

High

1162998

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1245181

E41L5
Band 4.1-like protein 5

1

3

High-throughput

0.536

High

443074

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.513

High

1245166

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.513

High

1245183

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

1

0

High-throughput

0.513

High

175086

SC16A
Protein transport protein Sec16A

1

11

High-throughput

0.489

High

255649

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

1

1

High-throughput

0.489

High

333677

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

1

High-throughput

0.489

High

483128

CLCA
Clathrin light chain A

1

1

High-throughput

0.489

High

483355

CLCB
Clathrin light chain B

1

1

High-throughput

0.489

High

772862

MYH9
Myosin-9

1

1

High-throughput

0.489

High

1150995

PCH2
Pachytene checkpoint protein 2 homolog

1

1

High-throughput

0.489

High

1245187

E41L3
Band 4.1-like protein 3

1

6

High-throughput

0.489

High

1245173

ESR2
Estrogen receptor beta

1

20

High-throughput

0.484

High

129192

MEN1
Menin

1

2

High-throughput

0.479

High

132107

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

6

High-throughput

0.479

High

181526

TBXT
T-box transcription factor T

1

13

High-throughput

0.479

High

194240

R113A
E3 ubiquitin-protein ligase RNF113A

1

5

High-throughput

0.479

High

210029

CRX
Cone-rod homeobox protein

1

11

High-throughput

0.479

High

225031

TLX3
T-cell leukemia homeobox protein 3

1

19

High-throughput

0.479

High

226561

TLX2
T-cell leukemia homeobox protein 2

1

10

High-throughput

0.479

High

406297

MYCN
N-myc proto-oncogene protein

1

10

High-throughput

0.479

High

419040

H2A1B
Histone H2A type 1-B/E

1

15

High-throughput

0.479

High

538418

EGR2
E3 SUMO-protein ligase EGR2

1

3

High-throughput

0.479

High

540892

ERG
Transcriptional regulator ERG

1

3

High-throughput

0.479

High

581672

MYOD1
Myoblast determination protein 1

1

5

High-throughput

0.479

High

588959

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

662238

PAX7
Paired box protein Pax-7

1

9

High-throughput

0.479

High

662444

GATA2
Endothelial transcription factor GATA-2

1

15

High-throughput

0.479

High

662596

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

15

High-throughput

0.479

High

685238

PAX6
Paired box protein Pax-6

1

7

High-throughput

0.479

High

695745

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

703157

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

725269

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

768466

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

775866

HNF1B
Hepatocyte nuclear factor 1-beta

1

10

High-throughput

0.479

High

833972

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

862233

YAP1
Transcriptional coactivator YAP1

1

8

High-throughput

0.479

High

873094

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

886969

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.479

High

938461

PAX9
Paired box protein Pax-9

1

7

High-throughput

0.479

High

942441

GSC
Homeobox protein goosecoid

1

9

High-throughput

0.479

High

944686

KLF3
Krueppel-like factor 3

1

13

High-throughput

0.479

High

979852

H4
Histone H4

1

5

High-throughput

0.479

High

980858

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

1016959

H33
Histone H3.3

1

20

High-throughput

0.479

High

1032013

TFAP4
Transcription factor AP-4

1

1

Small-scale

0.479

High

1040053

PAX2
Paired box protein Pax-2

1

7

High-throughput

0.479

High

1045414

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

1048009

TLE3
Transducin-like enhancer protein 3

1

9

High-throughput

0.479

High

1052880

HME1
Homeobox protein engrailed-1

1

4

High-throughput

0.479

High

1056617

PAX8
Paired box protein Pax-8

1

7

High-throughput

0.479

High

1091302

FOXL1
Forkhead box protein L1

1

9

High-throughput

0.479

High

1113442

CUL3
Cullin-3

1

7

High-throughput

0.479

High

1129628

MDC1
Mediator of DNA damage checkpoint protein 1

1

8

High-throughput

0.479

High

1160859

TBR1
T-box brain protein 1

1

13

High-throughput

0.479

High

1245167

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1245170

NUP43
Nucleoporin Nup43

1

20

High-throughput

0.479

High

1245172

SP7
Transcription factor Sp7

1

8

High-throughput

0.479

High

1245176

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.479

High

1245178

FEV
Protein FEV

1

3

High-throughput

0.479

High

1245180

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1245182

GCM1
Chorion-specific transcription factor GCMa

1

1

High-throughput

0.479

High

1245184

LHX3
LIM/homeobox protein Lhx3

1

2

High-throughput

0.479

High

1245185

ELF5
ETS-related transcription factor Elf-5

1

4

High-throughput

0.479

High

1245171

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1245189

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1099123

SRSF5
Serine/arginine-rich splicing factor 5

1

2

High-throughput

0.445

High

1245188

RBMX2
RNA-binding motif protein, X-linked 2

1

3

High-throughput

0.445

High

272269

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.437

High

341599

EYA4
Protein phosphatase EYA4

1

6

High-throughput

0.437

High

401012

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.437

High

986507

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.437

High

989747

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

1

High-throughput

0.437

High

1245165

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1245175

SH3K1
SH3 domain-containing kinase-binding protein 1

1

2

High-throughput

0.437

High

290603

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.426

High

591313

CD44
CD44 antigen

1

2

High-throughput

0.407

High

616764

SDC1
Syndecan-1

1

2

High-throughput

0.407

High

649339

H1T
Histone H1t

1

4

High-throughput

0.407

High

1034586

AK17A
A-kinase anchor protein 17A

1

1

High-throughput

0.407

High

1207498

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

1

High-throughput

0.407

High

1245169

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.407

High

467927

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

High-throughput

0.279

Low

1245168

AVL9
Late secretory pathway protein AVL9 homolog

1

0

High-throughput

0.279

Low

1245186

SNX12
Sorting nexin-12

1

0

High-throughput

0.279

Low

378499

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.249

Low

898697

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.232

Low

985214

RL10A
Large ribosomal subunit protein uL1

1

0

High-throughput

0.232

Low

1037529

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025