HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: MIER3 (Q7Z3K6)
Mesoderm induction early response protein 3 (Mi-er3)
Gene: MIER3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 550
+	Hs
		419050 H2A1B_HUMAN (1-129): 8.38e-66: 197: 90.70		MIER3_HUMAN (1-550): 1.74e-165: 483: 100.00
+	Hs
		502408 H2A1_HUMAN (1-129): 7.6e-66: 197: 91.47		MIER3_HUMAN (1-550): 1.74e-165: 483: 100.00
+	Hs
		1162814 H2A2C_HUMAN (1-129): 5.12e-65: 195: 90.70		MIER3_HUMAN (1-550): 1.74e-165: 483: 100.00
+	Hs
		1277273 H2AJ_HUMAN (1-125): 5.65e-65: 195: 93.60		MIER3_HUMAN (1-550): 1.74e-165: 483: 100.00
+	Hs
		591821 H2AX_HUMAN (1-143): 3.73e-74: 219: 100.00		MTA3_HUMAN (81-484): 5.7e-112: 347: 18.31
+	Hs
		591728 H2AX_HUMAN (1-143): 3.73e-74: 219: 100.00		MIER1_HUMAN (1-511): 1.95e-106: 330: 43.64
+	Hs
		591634 H2AX_HUMAN (1-143): 3.73e-74: 219: 100.00		MTA1_HUMAN (102-511): 9.84e-99: 316: 16.63
+	Hs
		1232694 H2A2A_HUMAN (1-129): 7.03e-66: 197: 91.47		MIER1_HUMAN (1-511): 1.95e-106: 330: 43.64
+	Hs
		419079 H2A1B_HUMAN (1-129): 8.38e-66: 197: 90.70		MIER1_HUMAN (1-511): 1.95e-106: 330: 43.64
+	Hs
		502430 H2A1_HUMAN (1-129): 7.6e-66: 197: 91.47		MIER1_HUMAN (1-511): 1.95e-106: 330: 43.64
+	Hs
		1162830 H2A2C_HUMAN (1-129): 5.12e-65: 195: 90.70		MIER1_HUMAN (1-511): 1.95e-106: 330: 43.64
+	Hs
		1322544 H2AJ_HUMAN (1-125): 5.65e-65: 195: 93.60		MIER1_HUMAN (1-511): 1.95e-106: 330: 43.64
+	Hs
		316741 H2AX_HUMAN (1-143): 3.73e-74: 219: 100.00		MTA2_HUMAN (78-493): 5.55e-94: 302: 16.21
+	Hs
		277677 H2AY_HUMAN (1-142): 1.75e-61: 194: 60.69		MTA1_HUMAN (102-511): 9.84e-99: 316: 16.63
+	Hs
		277487 H2AY_HUMAN (1-142): 1.75e-61: 194: 60.69		MTA2_HUMAN (78-493): 5.55e-94: 302: 16.21
+	Hs
		591881 H2AX_HUMAN (1-143): 3.73e-74: 219: 100.00		RCOR1_HUMAN (142-524): 1.88e-71: 238: 17.22
+	Hs
		277846 H2AY_HUMAN (1-142): 1.75e-61: 194: 60.69		RCOR1_HUMAN (142-524): 1.88e-71: 238: 17.22
+	Hs
		419040 H2A1B_HUMAN (1-129): 8.38e-66: 197: 90.70		MDEAS_HUMAN (65-497): 3.51e-59: 214: 15.77