HitPredict

Interactor 1: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Interactor 2: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.833

The method score is based on:

Property Details
Experiments 25416956, 26451611
Identification Methods two hybrid, enzymatic study, pull down, x-ray crystallography, two hybrid array
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~PDZ, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005886 - plasma membrane
GO:0030165 - PDZ domain binding
GO:0030182 - neuron differentiation
GO:0046872 - metal ion binding
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 690
Hs

1 690
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+ Ce
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+ Rn
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024