Interactor 1: EMC5 (Q8N4V1)
ER membrane protein complex subunit 5 (Membrane magnesium transporter 1) (Transmembrane protein 32)
Gene: MMGT1

Interactor 2: EMC6 (Q9BV81)
ER membrane protein complex subunit 6 (Transmembrane protein 93)
Gene: EMC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.90 0.897

The method score is based on:

Property Details
Experiments 22119785, 27342126, 32296183, 33961781, unassigned1304, 32439656
Identification Methods affinity chromatography technology, two hybrid, validated two hybrid, anti tag coimmunoprecipitation, pull down, two hybrid prey pooling approach, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EMC6~MMgT
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane
GO:0072546 - EMC complex
Homologous interactions 0

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Last updated: 15 Jul 2024