HitPredict

Interactor 1: DWA2 (Q6NPN9)
WD repeat-containing protein DWA2 (Protein DWD HYPERSENSITIVE TO ABA 2)
Gene: DWA2

Interactor 2: CUL4 (Q8LGH4)
Cullin-4 (AtCUL4)
Gene: CUL4

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20525848
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0009738 - abscisic acid-activated signaling pathway GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 At			1 792
+	Hs
		1115353 SNR40_HUMAN (98-350): 3.57e-53: 180: 18.82		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		1114994 SNR40_HUMAN (98-350): 3.57e-53: 180: 18.82		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	Hs
		964929 WDR5_HUMAN (4-236): 2.06e-42: 151: 13.69		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		1115283 WDR5B_HUMAN (5-236): 2.49e-41: 149: 13.33		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		964928 WDR5_HUMAN (4-236): 2.06e-42: 151: 13.69		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	Hs
		1114921 WDR5B_HUMAN (5-236): 2.49e-41: 149: 13.33		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	At
		198878 MSI1_ARATH (153-347): 1.13e-27: 114: 15.96		CUL4_ARATH (1-792): 0: 942: 100.00
+	Hs
		1066296 RBBP4_HUMAN (4-150): 6.52e-24: 103: 15.13		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		845298 LIS1_HUMAN (4-151): 4.68e-24: 103: 12.20		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		1115217 RBBP7_HUMAN (5-150): 3.01e-23: 101: 15.23		CUL4B_HUMAN (29-792): 0: 923: 55.95
+	Hs
		1066295 RBBP4_HUMAN (4-150): 6.52e-24: 103: 15.13		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	Hs
		845297 LIS1_HUMAN (4-151): 4.68e-24: 103: 12.20		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	Hs
		1114851 RBBP7_HUMAN (5-150): 3.01e-23: 101: 15.23		CUL4A_HUMAN (34-792): 0: 914: 55.79
+	Hs
		964927 WDR5_HUMAN (4-236): 2.06e-42: 151: 13.69		CUL3_HUMAN (60-792): 0: 833: 38.63
+	Hs
		1066294 RBBP4_HUMAN (4-150): 6.52e-24: 103: 15.13		CUL3_HUMAN (60-792): 0: 833: 38.63
+	Hs
		1113213 RBBP7_HUMAN (5-150): 3.01e-23: 101: 15.23		CUL3_HUMAN (60-792): 0: 833: 38.63
+	Hs
		1114438 NLE1_HUMAN (235-349): 1.51e-19: 91.4: 15.65		CUL3_HUMAN (60-792): 0: 833: 38.63
+	Hs
		964926 WDR5_HUMAN (4-236): 2.06e-42: 151: 13.69		CUL1_HUMAN (93-792): 0: 757: 29.37
+	Ce
		1018564 LIN53_CAEEL (207-348): 2.32e-21: 96: 20.67		CUL1_CAEEL (80-792): 0: 687: 26.85
+	Ce
		1018565 LIN53_CAEEL (207-348): 2.32e-21: 96: 20.67		CUL2_CAEEL (63-792): 0: 665: 24.53