HitPredict

Interactor 1: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.543

Property	Details
Experiments	32235678, 37365982
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 410 Hs			1 759
+	Hs
		845298 LIS1_HUMAN (1-410): 1.19e-137: 401: 100.00		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1114950 POC1B_HUMAN (179-410): 1.89e-62: 210: 28.88		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		984104 GBB2_HUMAN (166-410): 4.44e-51: 176: 20.48		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		1115313 POC1B_HUMAN (179-410): 1.89e-62: 210: 28.88		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1115406 TBL1R_HUMAN (31-265): 5.9e-56: 193: 22.04		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1114921 WDR5B_HUMAN (327-410): 1.33e-20: 93.7: 27.38		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		1114994 SNR40_HUMAN (328-408): 1.04e-17: 85.6: 26.83		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		261407 TBL1X_HUMAN (22-181): 4.51e-27: 115: 12.94		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1113779 POC1B_HUMAN (179-410): 1.89e-62: 210: 28.88		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1115283 WDR5B_HUMAN (327-410): 1.33e-20: 93.7: 27.38		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1115353 SNR40_HUMAN (328-408): 1.04e-17: 85.6: 26.83		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1115343 FBXW7_HUMAN (323-408): 1.31e-15: 81: 33.33		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		984103 GBB2_HUMAN (166-410): 4.44e-51: 176: 20.48		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1114438 NLE1_HUMAN (1-219): 1.04e-43: 160: 22.51		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		222479 PLRG1_HUMAN (224-409): 2.03e-43: 160: 24.73		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Mm
		1353853 FBXW7_MOUSE (1-257): 6.4e-43: 161: 20.68		CUL1_MOUSE (59-759): 0: 740: 30.55
+	Hs
		992736 RACK1_HUMAN (103-261): 2.67e-16: 80.9: 33.13		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1112642 FBXW7_HUMAN (323-408): 1.31e-15: 81: 33.33		CUL1_HUMAN (59-759): 0: 740: 30.55
+	Hs
		992734 RACK1_HUMAN (103-261): 2.67e-16: 80.9: 33.13		CUL1_HUMAN (59-759): 0: 740: 30.55
+	Hs
		992735 RACK1_HUMAN (103-261): 2.67e-16: 80.9: 33.13		CUL2_HUMAN (51-759): 0: 706: 27.26