HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32235678, 17079684
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Hs			1 759
+	Hs
		1066296 RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1114921 WDR5B_HUMAN (92-418): 3.46e-69: 223: 18.49		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		1066294 RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1115283 WDR5B_HUMAN (92-418): 3.46e-69: 223: 18.49		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1114950 POC1B_HUMAN (2-229): 2.7e-50: 178: 12.45		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		1115313 POC1B_HUMAN (2-229): 2.7e-50: 178: 12.45		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1114851 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		964928 WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		1115030 GRWD1_HUMAN (263-425): 9.87e-26: 110: 23.56		CUL4A_HUMAN (1-759): 0: 958: 100.00
+	Hs
		1115217 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		964929 WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1115386 GRWD1_HUMAN (263-425): 9.87e-26: 110: 23.56		CUL4B_HUMAN (10-759): 0: 922: 82.31
+	Hs
		1113779 POC1B_HUMAN (2-229): 2.7e-50: 178: 12.45		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1113186 TAF5_HUMAN (2-226): 1.24e-38: 150: 15.22		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1113213 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		964927 WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1114131 GRWD1_HUMAN (263-425): 9.87e-26: 110: 23.56		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		1114438 NLE1_HUMAN (3-106): 1.73e-23: 104: 10.09		CUL3_HUMAN (32-759): 0: 810: 38.23
+	Hs
		964926 WDR5_HUMAN (267-425): 2.01e-35: 135: 25.61		CUL1_HUMAN (59-759): 0: 740: 30.55
+	Hs
		1112685 GRWD1_HUMAN (263-425): 9.87e-26: 110: 23.56		CUL1_HUMAN (59-759): 0: 740: 30.55