Interactor 1: SPT5H (O00267)
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)
Gene: SUPT5H
Interactor 2: SPT4H (P63272)
Transcription elongation factor SPT4 (hSPT4) (DRB sensitivity-inducing factor 14 kDa subunit) (DSIF p14) (DRB sensitivity-inducing factor small subunit) (DSIF small subunit)
Gene: SUPT4H1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30217970, 27107012, 24981860, 19860741, 26496610, 12718890, 29395067, 35271311, 12653964, 10075709, 17404243, 26789250, 25416956, 25502805, 31515488 |
| Identification Methods | two hybrid, affinity chromatography technology, x-ray crystallography, proximity labelling technology, biochemical, pull down, molecular sieving, cross-linking study, mammalian protein protein interaction trap, barcode fusion genetics two hybrid and 6 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | KOW~Spt4, Spt4~Spt5-NGN |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0032044 - DSIF complex and 6 others more... |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
