HitPredict - High confidence protein-protein interactions

Interactor 1: JMJD6 (Q6NYC1)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)
Gene: JMJD6

Interactor 2: JMJD6 (Q6NYC1)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)
Gene: JMJD6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	24360279
Identification Methods	comigration in sds page
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	JmjC~JmjC
Common GO terms	GO:0001822 - kidney development GO:0002040 - sprouting angiogenesis GO:0003723 - RNA binding GO:0003727 - single-stranded RNA binding GO:0005506 - iron ion binding and 36 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006338 - chromatin remodeling GO:0006397 - mRNA processing GO:0006909 - phagocytosis GO:0007166 - cell surface receptor signaling pathway GO:0007507 - heart development GO:0008380 - RNA splicing GO:0018395 - peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine GO:0030324 - lung development GO:0032452 - histone demethylase activity GO:0032463 - negative regulation of protein homooligomerization GO:0033077 - T cell differentiation in thymus GO:0033746 - histone H3R2 demethylase activity GO:0033749 - histone H4R3 demethylase activity GO:0035513 - oxidative RNA demethylation GO:0035515 - oxidative RNA demethylase activity GO:0038023 - signaling receptor activity GO:0042116 - macrophage activation GO:0043654 - recognition of apoptotic cell GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048024 - regulation of mRNA splicing, via spliceosome GO:0048821 - erythrocyte development GO:0051260 - protein homooligomerization GO:0060041 - retina development in camera-type eye GO:0070815 - peptidyl-lysine 5-dioxygenase activity GO:0106140 - P-TEFb complex binding GO:0140457 - protein demethylase activity GO:0140537 - transcription regulator activator activity GO:0140694 - membraneless organelle assembly GO:1990904 - ribonucleoprotein complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	403
Hs

1	403

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Last updated: 11Aug2025