Interactor 1: SPT5H (O00267)
Transcription elongation factor SPT5 (hSPT5) (DRB sensitivity-inducing factor 160 kDa subunit) (DSIF p160) (DRB sensitivity-inducing factor large subunit) (DSIF large subunit) (Tat-cotransactivator 1 protein) (Tat-CT1 protein)
Gene: SUPT5H

Interactor 2: SPT6H (Q7KZ85)
Transcription elongation factor SPT6 (hSPT6) (Histone chaperone suppressor of Ty6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein)
Gene: SUPT6H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26496610, 29395067, 35271311
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KOW~S1
Common GO terms GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0006368 - transcription elongation by RNA polymerase II
GO:0140673 - transcription elongation-coupled chromatin remodeling
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1087
Hs

1 1726
+ Dm
+ Sc
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024