HitPredict

Interactor 1: EDC4 (Q6P2E9)
Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls)
Gene: EDC4

Interactor 2: DCP1B (Q8IZD4)
mRNA-decapping enzyme 1B (EC 3.6.1.62)
Gene: DCP1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.692

The method score is based on:

Property Details
Experiments 35688132, 21672539, 24981860, 25036637
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000932 - P-body
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016020 - membrane
GO:0031087 - deadenylation-independent decapping of nuclear-transcribed mRNA
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1401
Hs

1 617
+ Hs
+ Dm
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025