Interactor 1: PK3C3 (Q8NEB9)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34)
Gene: PIK3C3

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 20921139, 20417604
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~WD40
Common GO terms GO:0000045 - autophagosome assembly
GO:0005737 - cytoplasm
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0005930 - axoneme
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 887
Hs

1 1298
+ Mm
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024